cis-Montelukast

Base Information

• Chemical Name: cis-Montelukast
• CAS No.: 774538-96-4
• Molecular Formula: C35H36ClNO3S
• Molecular Weight: 586.18324
• Mol file: 774538-96-4.mol

Synonyms:cis-Montelukast;1-[[[(1R)-1-[3-[(1Z)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-Methylethyl)phenyl]propyl]thio]Methyl]cyclopropaneacetic Acid;Montelukast EP IMpurity G

Chemical Property of cis-Montelukast

Chemical Property:

• Melting Point: 58-71°C
• PSA: 95.72000
• Density: 1.272
• LogP: 8.94800
• Storage Temp.: Amber Vial, -20?C Freezer, Under Inert Atmosphere
• Solubility.: Dichloromethane (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

98%Min ^*data from raw suppliers

cis-Montelukast ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: cis-Montelukast (Montelukast EP Impurity G; Montelukast USP Related Compound G; Montelukast cis Isomer) is a cis geometric isomer of Montelukast. An impurity of Montelukast. The cis geometric isomer of Montelukast. An impurity of Montelukast.

Technology Process of cis-Montelukast

There total 1 articles about cis-Montelukast which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Montelukast sodium (151767-02-1) → 1-[[[(1R)-1-[3-[(lZ)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (774538-96-4)

Guidance literature:

Montelukast sodium; In methanol; for 96h; Inert atmosphere; Sunlight;

With formic acid; In water; acetonitrile;

With sodium hydrogencarbonate; In water; pH=7 - 8;

upstream raw materials:

Montelukast sodium

Refernces