SteMRegenin 1

Base Information

• Chemical Name: SteMRegenin 1
• CAS No.: 1227633-49-9
• Molecular Formula: C24H23N5OS
• Molecular Weight: 429.546
• Hs Code.: 2934999090
• Mol file: 1227633-49-9.mol

Synonyms:4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylaMino)ethyl)phenol;Phenol, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-Methylethyl)-9H-purin-6-yl]aMino]ethyl]-;

Chemical Property of SteMRegenin 1

Chemical Property:

• Boiling Point: 604.9±65.0 °C(Predicted)
• PKA: 10.03±0.15(Predicted)
• PSA: 104.10000
• Density: 1.36±0.1 g/cm3(Predicted)
• LogP: 5.72210
• Storage Temp.: +2C to +8C
• Solubility.: Soluble in DMSO (up to 10 mg/ml).

Purity/Quality:

99% ^*data from raw suppliers

AhR Antagonist II, SR1 ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Description: SR1 (1227633-49-9)?extends the pluripotency of hematopoietic stem cells by antagonizing the arylhydrocarbon receptor (AhR), IC50?= 127?nM.1?The effect is dose-dependent and reversible. Displays a biphasic effect on CD34-negative cells with low does (1 μM) enhancing proliferation and high does (>5 μM) repressing proliferation.2?May be used to generate progenitor T cells3?from HSPCs as well as NK cells for immuno-oncology studies4.

Technology Process of SteMRegenin 1

There total 1 articles about SteMRegenin 1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ StemRegenin1 (1227633-49-9)

Guidance literature:

Reference yield:

StemRegenin1 (1227633-49-9) → 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol sulfate

Guidance literature:

With sulfuric acid; In water; acetone; at 20 - 55 ℃; for 18.5h;

Reference yield:

StemRegenin1 (1227633-49-9) → 4-(2-(2-(benzo[b]thiophen-3-yl)-9-isopropyl-9H-purin-6-ylamino)ethyl)phenol hydrobromide

Guidance literature:

With hydrogen bromide; In N,N-dimethyl-formamide; at 20 - 65 ℃; for 18.5h;

Refernces

• 1、 -. "Enhancement of Natural Killer (NK) Cell Proliferation and Activity". . . Retrieved 2014/02/16.