2-[2-(Dimethylamino)ethoxy]ethanol

Base Information

• Chemical Name: 2-[2-(Dimethylamino)ethoxy]ethanol
• CAS No.: 1704-62-7
• Deprecated CAS: 136363-88-7,314270-53-6,1985590-30-4
• Molecular Formula: C6H15NO2
• Molecular Weight: 133.191
• Hs Code.: 29225090
• European Community (EC) Number: 216-940-1
• NSC Number: 3146
• UNII: C3YTX3O172
• DSSTox Substance ID: DTXSID1027427
• Nikkaji Number: J24.982C
• Wikidata: Q27275154
• ChEMBL ID: CHEMBL3188351
• Mol file: 1704-62-7.mol

Synonyms:2-(2-dimethylaminoethoxy)ethanol

Chemical Property of 2-[2-(Dimethylamino)ethoxy]ethanol

Chemical Property:

• Appearance/Colour: liquid
• Vapor Pressure: 0.173mmHg at 25°C
• Refractive Index: n20/D 1.442(lit.)
• Boiling Point: 194.8 °C at 760 mmHg
• PKA: 14.37±0.10(Predicted)
• Flash Point: 71.6 °C
• PSA: 32.70000
• Density: 0.954 g/cm³
• LogP: -0.44310
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: 1000g/L at 20℃
• XLogP3: -0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 133.110278721
• Heavy Atom Count: 9
• Complexity: 57

Purity/Quality:

99.9% ^*data from raw suppliers

2-[2-(Dimethylamino)ethoxy]ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 21-41
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)CCOCCO
• Uses: Used for the preparation of low-density packaging foams.

Technology Process of 2-[2-(Dimethylamino)ethoxy]ethanol

There total 16 articles about 2-[2-(Dimethylamino)ethoxy]ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.5%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-(2-Aminoethoxy)ethanol (929-06-6) → 1-O-Dimethylaminoethyl-ethylenglykol (1704-62-7)

Guidance literature:

formaldehyd; 2-(2-Aminoethoxy)ethanol; for 0.5h;

With formic acid; at 100 - 110 ℃; for 2h; under 705.071 Torr;

With butan-1-ol; at 120 ℃; for 4h; Reagent/catalyst; Temperature;

Reference yield: 92.3%

oxirane (75-21-8,99932-75-9) + dimethyl amine (124-40-3) → 2-(N,N-dimethylamino)ethanol (108-01-0) + 1-O-Dimethylaminoethyl-ethylenglykol (1704-62-7)

Guidance literature:

In water; at 80 ℃; for 0.025h; Temperature;

Reference yield: 92.3%

oxirane (75-21-8,99932-75-9) + dimethyl amine (124-40-3) → 1-O-Dimethylaminoethyl-ethylenglykol (1704-62-7) + 1-O<2'-Dimethylaminoethoxyethyl>ethylenglykol (2741-30-2)

Guidance literature:

In water; at 80 ℃; for 0.025h; Temperature;

upstream raw materials:

oxirane

2-(N,N-dimethylamino)ethanol

dimethyl amine

2-(2-Chloroethoxy)ethanol

Downstream raw materials:

2'-O-[2-(2-(N,N-dimethylamino)ethoxy)ethyl]-5-methyluridine

phenol

2-(2-dimethylaminoethoxy)ethoxo(methoxo)tetraphenylporphyrinatoantimony(V) bromide

4-{2-[2-(dimethylamino)ethoxy]ethoxy}phthalonitrile

Refernces

• 1、 Feng, Lifang,Shi, Yugang,Tian, Shiyi,Yang, Yuexi. "Coupling of Bioreaction and Separation via Novel Thermosensitive Ionic Liquids Applied in the Baker’s Yeast-Catalyzed Reduction of Ethyl 2-oxo-4-phenylbutyrate". . . Retrieved 2020.
• 2、 -. "Integrated preparation method of DMAE and DMAEE in microtubule reactor". Paragraph 0035-0036; 0042. . Retrieved 2018/03/23.