BRD4770

Base Information

• Chemical Name: BRD4770
• CAS No.: 1374601-40-7
• Molecular Formula: C25H23N3O3
• Molecular Weight: 413.47
• Mol file: 1374601-40-7.mol

Synonyms:BRD4770;methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate;methyl 2-benzamido-1-(3-phenylpropyl)-1H-benzo[d]imidazole-5-carboxylate BRD4770;2-(Benzoylamino)-1-(3-phenylpropyl)-1H-benzimidazole-5-carboxylic acid methyl ester

Chemical Property of BRD4770

Chemical Property:

• PKA: 12.12±0.43(Predicted)
• PSA: 73.22000
• Density: 1.21±0.1 g/cm3(Predicted)
• LogP: 4.78100
• Storage Temp.: 2-8°C
• Solubility.: DMSO: soluble5mg/mL, clear (warmed)

Purity/Quality:

98%,99%, ^*data from raw suppliers

BRD-4770 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

Useful:

• Uses: BRD4770 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, decreasing di- and trimethylation on lysine 9 of histone 3 (EC50 = 5 μM). Through its effects on EHMT2, BRD4770 induces senescence in the pancreatic cancer cell line PANC-1 without initiating apoptosis. It also blocks both anchorage-dependent and –independent proliferation of PANC-1 cells.[Cayman Chemical]