CID 13206344

Base Information

• Chemical Name: CID 13206344
• CAS No.: 3847-29-8
• Molecular Formula: C₁₂H₂₂O₁₂*C₃₇H₆₇NO₁₃
• Molecular Weight: 1092.24
• Hs Code.: 2941500000
• European Community (EC) Number: 223-348-7
• NCI Thesaurus Code: C47988
• RXCUI: 24347
• Mol file: 3847-29-8.mol

Synonyms:erythromycin lactobionate

Chemical Property of CID 13206344

Chemical Property:

• Vapor Pressure: 4.94E-31mmHg at 25°C
• Melting Point: 145-150°
• Refractive Index: 1.5300 (estimate)
• Boiling Point: 818.4 °C at 760 mmHg
• Flash Point: 448.8 °C
• PSA: 411.51000
• Density: 0.9083 (rough estimate)
• LogP: -3.88330
• Storage Temp.: Refrigerator
• Solubility.: Soluble in water, freely soluble in anhydrous ethanol and in methanol, very slightly soluble in acetone and in methylene chloride.
• Water Solubility.: >20g/L(21 oC)
• Hydrogen Bond Donor Count: 14
• Hydrogen Bond Acceptor Count: 26
• Rotatable Bond Count: 15
• Exact Mass: 1091.57236732
• Heavy Atom Count: 75
• Complexity: 1580

Purity/Quality:

99% ^*data from raw suppliers

ErythromycinLactobionate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
• Recent ClinicalTrials: ANTERO-4: VIPUN Gastric Monitoring System in an Erythromycin Model
• Recent EU Clinical Trials: The Impact of Target Temperature Management on Drug Metabolism
• Description: Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
• Uses: Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs. Macrolide antibacterial.
• Therapeutic Function: Antibacterial

Technology Process of CID 13206344

There total 1 articles about CID 13206344 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

erythromycin (114-07-8) + lactobionic acid (96-82-2,534-41-8,534-42-9,51267-45-9,58459-39-5,69728-97-8,21675-39-8) → erythromycin lactobionate (3847-29-8,69779-46-0)

Guidance literature:

With water; at 5 - 40 ℃; Product distribution / selectivity;

upstream raw materials:

erythromycin

lactobionic acid

Refernces