Hexafluoroisopropyl acrylate

Base Information

• Chemical Name: Hexafluoroisopropyl acrylate
• CAS No.: 2160-89-6
• Deprecated CAS: 151165-63-8
• Molecular Formula: C6H4F6O2
• Molecular Weight: 222.087
• Hs Code.: 29161290
• European Community (EC) Number: 218-479-1
• DSSTox Substance ID: DTXSID10880178
• Nikkaji Number: J254.866F
• Wikidata: Q72481722
• Mol file: 2160-89-6.mol

Synonyms:2160-89-6;1,1,1,3,3,3-Hexafluoroisopropyl acrylate;Hexafluoroisopropyl acrylate;1,1,1,3,3,3-hexafluoropropan-2-yl acrylate;1,1,1,3,3,3-hexafluoropropan-2-yl prop-2-enoate;HFIPA;2-Propenoic acid, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester;1,1,1,3,3,3-Hexafluoroisopropyl Acrylate (stabilized with TBC);Acrylic Acid 1,1,1,3,3,3-Hexafluoroisopropyl Ester;C6H4F6O2;SCHEMBL62949;MNSWITGNWZSAMC-UHFFFAOYSA-;DTXSID10880178;EINECS 218-479-1;MFCD00040104;AKOS005257995;FS-4423;A1146;FT-0605917;H1582;1,1,1,3,3,3-hexafluoropropan-2-ylacrylate;D86398;1,1,1,3,3,3-Hexafluoroisopropyl acrylate, 99%;A815519;2,2,2-Trifluoro-1-(trifluoromethyl)ethyl acrylate;alpha-trifluoromethyl-2,2,2-trifluoroethyl acrylate;J-014172;2,2,2-Trifluoro-1-(trifluoromethyl)ethyl acrylate #;1,1,1,3,3,3-Hexafluoroisopropyl Acrylate, (stabilized with MEHQ)

Chemical Property of Hexafluoroisopropyl acrylate

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 1.22 psi ( 20 °C)
• Refractive Index: n20/D 1.319(lit.)
• Boiling Point: 110.3 °C at 760 mmHg
• Flash Point: 10 °C
• PSA: 26.30000
• Density: 1.394 g/cm³
• LogP: 2.20880
• Storage Temp.: Flammables area
• Water Solubility.: Insoluble
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 222.01154834
• Heavy Atom Count: 14
• Complexity: 214

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1,1,3,3,3-Hexafluoroisopropyl acrylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi,N,F
• Hazard Codes: Xi,N,F
• Statements: 36/37/38-51/53-11
• Safety Statements: 26-28-61-37/39-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(=O)OC(C(F)(F)F)C(F)(F)F
• Uses: 1,1,1,3,3,3-Hexafluoroisopropyl acrylate is used in agrochemical, pharmaceutical and dyestuff field.

Technology Process of Hexafluoroisopropyl acrylate

There total 2 articles about Hexafluoroisopropyl acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1,1,3',3',3'-hexafluoro-propanol (920-66-1) + acryloyl chloride (814-68-6,25189-84-8) → 1,1,1,3,3,3-hexafluoroisopropyl acrylate (2160-89-6)

Guidance literature:

With scandium tris(trifluoromethanesulfonate); at 20 ℃; for 20.0833h;

Reference yield:

→ 1,1,1,3,3,3-hexafluoroisopropyl acrylate (2160-89-6)

Guidance literature:

Acrylic acid, trifluoroacetic anhydride, 2H-hexafluoro-propan-2-ol;

Reference yield: 95.0%

iodobenzene (591-50-4) + 1,1,1,3,3,3-hexafluoroisopropyl acrylate (2160-89-6) → (E)-3-Phenyl-acrylic acid 2,2,2-trifluoro-1-trifluoromethyl-ethyl ester

Guidance literature:

With PdAS-V; triethylamine; In toluene; at 100 ℃; for 5h;

DOI:10.1016/S0040-4039(03)00220-X

upstream raw materials:

1,1,1,3',3',3'-hexafluoro-propanol

acryloyl chloride

Downstream raw materials:

1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-hydroxy-2-methylene-3-phenylpropanoate

1,1,1,3,3,3-hexafluoropropan-2-yl (R)-3-cyclohexyl-3-hydroxy-2-methylenepropanoate

methyl (S)-2-methanesulfonylamino-2-phenylacetate

Refernces