Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI)

Base Information

• Chemical Name: Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI)
• CAS No.: 81864-39-3
• Molecular Formula: C10H10N2S
• Molecular Weight: 190.269
• Mol file: 81864-39-3.mol

Synonyms:Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI)

Chemical Property of Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI)

Chemical Property:

• Melting Point: 300 °C
• PSA: 67.48000
• LogP: 2.34030

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI)

There total 6 articles about Indeno[5,6-d]imidazole-2(1H)-thione, 3,5,6,7-tetrahydro- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

indan-5-amine (24425-40-9) → 2-mercaptocyclopentano<1,2-f>benzimidazole (81864-39-3)

Guidance literature:

Multi-step reaction with 5 steps

1: 2 h / 110 °C

2: nitric acid / 0 - 5 °C

3: 10 M NaOH

4: H₂ / Pd/C / ethanol

5: ethanol; H₂O / 12 h / Heating

With sodium hydroxide; hydrogen; nitric acid; palladium on activated charcoal; In ethanol; water;

DOI:10.1021/jm00025a008

Reference yield:

5-amino-6-nitroindane (52957-66-1) → 2-mercaptocyclopentano<1,2-f>benzimidazole (81864-39-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C / ethanol

2: ethanol; H₂O / 12 h / Heating

With hydrogen; palladium on activated charcoal; In ethanol; water;

DOI:10.1021/jm00025a008

Reference yield:

5-acetamino-6-nitro-indane (55491-36-6) → 2-mercaptocyclopentano<1,2-f>benzimidazole (81864-39-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 10 M NaOH

2: H₂ / Pd/C / ethanol

3: ethanol; H₂O / 12 h / Heating

With sodium hydroxide; hydrogen; palladium on activated charcoal; In ethanol; water;

DOI:10.1021/jm00025a008

upstream raw materials:

5R,6R-trans-5,6-diaminoindan

potassium ethyl xanthogenate

indan-5-amine

5-amino-6-nitroindane

Downstream raw materials:

2-(4-Methoxy-3-methyl-pyridin-2-ylmethylsulfanyl)-1,5,6,7-tetrahydro-indeno[5,6-d]imidazole

Refernces

• 1、 -. "Imidazole derivatives". . . Retrieved 2008/06/13.