2-Hydroxy-3-((1-hydroxy-2-methylpropan-2-yl)amino)propane-1-sulfonic acid

Base Information

• Chemical Name: 2-Hydroxy-3-((1-hydroxy-2-methylpropan-2-yl)amino)propane-1-sulfonic acid
• CAS No.: 68399-79-1
• Molecular Formula: C7H17NO5S
• Molecular Weight: 227.282
• Hs Code.: 29221990
• European Community (EC) Number: 269-991-7
• NSC Number: 378146
• DSSTox Substance ID: DTXSID60887354
• Nikkaji Number: J349.394F
• Mol file: 68399-79-1.mol

Synonyms:3-((1,1-dimethyl-2-hydroxyethyl)amino)-2-hydroxypropanesulfonic acid;AMPSO compound

Chemical Property of 2-Hydroxy-3-((1-hydroxy-2-methylpropan-2-yl)amino)propane-1-sulfonic acid

Chemical Property:

• Appearance/Colour: white crystalline powder
• Melting Point: ~222 °C
• Refractive Index: 1.529
• PKA: 9.0(at 25℃) 9.1(at 37℃)
• PSA: 115.24000
• Density: 1.361 g/cm³
• LogP: 0.06730
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: Soluble in water (333.33 mg/ml, clear to slightly hazy colorless solution).
• XLogP3: -4.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 227.08274382
• Heavy Atom Count: 14
• Complexity: 256

Purity/Quality:

99%, ^*data from raw suppliers

AMPSO ≥99% (titration) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: CC(C)(CO)NCC(CS(=O)(=O)O)O
• Uses: It is used as an alkaline transfer buffer used for the transfer of strongly basic proteins from gels to nitrocellulose.

Technology Process of 2-Hydroxy-3-((1-hydroxy-2-methylpropan-2-yl)amino)propane-1-sulfonic acid

There total 2 articles about 2-Hydroxy-3-((1-hydroxy-2-methylpropan-2-yl)amino)propane-1-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Amino-2-methyl-1-propanol (124-68-5) → 3-<(1,1-dimethyl-2-hydroxyethyl)amino>-2-hydroxypropanesulfonic acid (68399-79-1)

Guidance literature:

Reference yield:

→ 3-<(1,1-dimethyl-2-hydroxyethyl)amino>-2-hydroxypropanesulfonic acid (68399-79-1)

Guidance literature:

upstream raw materials:

2-Amino-2-methyl-1-propanol

Refernces

• 1、 -. "Amino-hydroxy-alkyl sulfonic acid zwitterions". . . Retrieved 2008/06/13.