4-Indanol

Base Information

• Chemical Name: 4-Indanol
• CAS No.: 1641-41-4
• Molecular Formula: C9H10 O
• Molecular Weight: 134.178
• Hs Code.: 2907199090
• European Community (EC) Number: 216-691-9
• NSC Number: 64460
• UNII: 7PJT17BE05
• DSSTox Substance ID: DTXSID00167708
• Nikkaji Number: J136.395F
• Wikidata: Q83037137
• Mol file: 1641-41-4.mol

Synonyms:4-Indanol;1641-41-4;2,3-dihydro-1H-inden-4-ol;Indan-4-ol;1H-Inden-4-ol, 2,3-dihydro-;4-hydroxyindan;MFCD00053431;7PJT17BE05;EINECS 216-691-9;NSC 64460;NSC-64460;4-hydroxyindane;4-HYDROXYHYDRINDENE;NCIOpen2_000216;UNII-7PJT17BE05;SCHEMBL154077;DTXSID00167708;AMY22921;NSC64460;AKOS006273247;CS-W006868;DS-12894;SY107623;FT-0740725;EN300-157277;J-515537;Z1198149277;PyBroP?Bromo-tris-pyrrolidinophosphonium hexafluorophosphate

Chemical Property of 4-Indanol

Chemical Property:

• Melting Point: 47-51 °C
• Boiling Point: 245.3°Cat760mmHg
• PKA: pK1:10.32 (25°C)
• Flash Point: 110.3°C
• PSA: 20.23000
• Density: 1.147g/cm³
• LogP: 1.88090
• Storage Temp.: 2-8°C
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 134.073164938
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

99% ^*data from raw suppliers

4-Indanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1)C(=CC=C2)O

Technology Process of 4-Indanol

There total 22 articles about 4-Indanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-(3-butenoyl)-2-vinylcyclopentene (1089665-40-6) → 4-indanol (1641-41-4)

Guidance literature:

With Blechert catalyst; In dichloromethane; at 40 ℃; for 12h; Inert atmosphere;

DOI:10.1002/chem.200800484

Reference yield: 90.0%

7-hydroxy-indan-1-one (6968-35-0) → 4-indanol (1641-41-4)

Guidance literature:

With triethylsilane; In trifluoroacetic acid;

Reference yield: 77.0%

1,2-diethynylcyclohex-1-ene (107300-32-3) → 4-indanol (1641-41-4)

Guidance literature:

With [(tris(1-pyrazolyl)borate)Ru(P(phenyl)3)(CH₃CN)2]PF₆; water; In various solvent(s); at 100 ℃; for 24h;

DOI:10.1021/ja043047j

upstream raw materials:

4-aminoindan

Spiro-<3.5>nona-6,8-dien-5-on

1-(2,3-dihydro-1H-inden-4-yl)ethanone

S-Methyl 2-<3-(Trimethylsilyl)-2-propenyl>cyclopentene-1-thioate

Downstream raw materials:

7-(3,4-dichloro-benzyl)-indan-4-ol

5,7-bis-(3,4-dichloro-benzyl)-indan-4-ol

7-(2,4-dichloro-benzyl)-indan-4-ol

5,7-bis-(2,4-dichloro-benzyl)-indan-4-ol

Refernces

• 1、 Karasawa, Masayuki,Shoji, Osami,Stanfield, Joshua Kyle,Suzuki, Kazuto,Yonemura, Kai. "Designer Outer Membrane Protein Facilitates Uptake of Decoy Molecules into a Cytochrome P450BM3-Based Whole-Cell Biocatalyst". supporting information. . Retrieved 2021/12/16.
• 2、 -. "BICYCLIC COMPOUNDS AS INHIBITORS OF PD1/PD-L1 INTERACTION/ACTIVATION". Paragraph 00098. . Retrieved 2019/10/04.