WAY100635

Base Information

• Chemical Name: WAY100635
• CAS No.: 1092679-51-0
• Molecular Formula: C25H34N4O2.C4H4O4
• Molecular Weight: 538.63522
• Mol file: 1092679-51-0.mol

Synonyms:Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (1:1);WAY-100635 (maleate) N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate

Chemical Property of WAY100635

Chemical Property:

• PSA: 123.51000
• LogP: 3.54040
• Solubility.: ≥53.9 mg/mL in DMSO; ≥51.2 mg/mL in EtOH; ≥6.08 mg/mL in H2O with ultrasonic

Purity/Quality:

98%,99%, ^*data from raw suppliers

WAY-100635 Maleate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and function of 5-HT1A receptors. However, WAY-100635 has also been shown to exhibit agonist activity at dopamine D4 receptors (Kd = 2.4 nM).