lithium benzofuran-2-sulfinate

Base Information

• Chemical Name: lithium benzofuran-2-sulfinate
• CAS No.: 124043-83-0
• Molecular Formula: C8H5LiO3S
• Molecular Weight: 188.1295
• Mol file: 124043-83-0.mol

Synonyms:lithium benzofuran-2-sulfinate

Chemical Property of lithium benzofuran-2-sulfinate

Chemical Property:

• PSA: 72.48000
• LogP: 2.53650

Purity/Quality:

98% ^*data from raw suppliers

Lithiumbenzofuran-2-sulfinate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of lithium benzofuran-2-sulfinate

There total 1 articles about lithium benzofuran-2-sulfinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-benzofurane (271-89-6) → lithium benzo[b]furan-2-sulfinate (124043-83-0)

Guidance literature:

1-benzofurane; With tert.-butyl lithium; In diethyl ether; at -78 ℃; Inert atmosphere;

With sulfur dioxide; In diethyl ether; at -78 - 23 ℃;

DOI:10.1002/chem.201204201

Reference yield: 89.0%

lithium benzo[b]furan-2-sulfinate (124043-83-0) + 4-cyanophenyl trifluoromethanesulfonate (66107-32-2) → 4-(1-benzofuran-2-yl)benzonitrile (41013-94-9)

Guidance literature:

With palladium(II) acetylacetonate; triphenylphosphine; In ethanol; at 150 ℃; for 1h; Solvent; Temperature; Microwave irradiation; Green chemistry;

DOI:10.3987/COM-14-S(K)104

Reference yield: 82.0%

lithium benzo[b]furan-2-sulfinate (124043-83-0) + 4-bromobenzenecarbonitrile (623-00-7) → 4-(1-benzofuran-2-yl)benzonitrile (41013-94-9)

Guidance literature:

With triphenylphosphine; palladium dichloride; In water; N,N-dimethyl-formamide; at 23 - 170 ℃; for 0.141667h; Concentration; Reagent/catalyst; Solvent; chemoselective reaction;

DOI:10.1039/c3nj41153b

upstream raw materials:

1-benzofurane

Downstream raw materials:

benzofuran-2-sulfonyl chloride

4-(1-benzofuran-2-yl)benzonitrile

Refernces

• 1、 Mangel, Daniel,Buonomano, Cindy,Svigny, Stphane,Di Censo, Gianna,Thevendran, Gowsic,Forgione, Pat. "Efficient desulfinative cross-coupling of heteroaromatic sulfinates with aryl triflates in environmentally friendly protic solvents". . p. 1228 - 1239. Retrieved 2015/03/04.
• 2、 Sévigny, Stéphane,Forgione, Pat. "Efficient desulfinylative cross-coupling of thiophene and furan sulfinates with aryl bromides in aqueous media". supporting information. p. 589 - 592. Retrieved 2013/04/10.