1-Methoxy-8-phenylnaphthalene

Base Information

• Chemical Name: 1-Methoxy-8-phenylnaphthalene
• CAS No.: 103392-94-5
• Molecular Formula: C17H14O
• Molecular Weight: 234.298
• Mol file: 103392-94-5.mol

Synonyms:1-Methoxy-8-phenylnaphthalene

Chemical Property of 1-Methoxy-8-phenylnaphthalene

Chemical Property:

• PSA: 9.23000
• LogP: 4.51540

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methoxy-8-phenylnaphthalene

There total 6 articles about 1-Methoxy-8-phenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

8-phenylnaphthalen-1-ol (129957-20-6) + dimethyl sulfate (77-78-1) → 1-methoxy-8-phenylnaphthalene (103392-94-5)

Guidance literature:

8-phenylnaphthalen-1-ol; With potassium carbonate; for 0.25h; Inert atmosphere;

dimethyl sulfate; In acetone; at 20 - 75 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.tet.2017.11.054

Reference yield: 78.0%

bromobenzene (108-86-1,52753-63-6) + 8-methoxy-naphthalen-1-ylboronic acid → 1-methoxy-8-phenylnaphthalene (103392-94-5)

Guidance literature:

8-methoxy-naphthalen-1-ylboronic acid; With sodium carbonate; In ethanol; water; toluene; at 20 ℃; for 1h;

bromobenzene; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; at 90 ℃; for 3h;

DOI:10.1246/bcsj.20110139

Reference yield: 58.0%

5-exo-(3-methoxyphenyl)-6-exo-(2-phenylethynyl)bicyclo[2.2.1]hept-2-ene → 1-methoxy-8-phenylnaphthalene (103392-94-5) + methyl-(5-phenyl-[2]naphthyl)-ether (27331-47-1)

Guidance literature:

With palladium diacetate; 2-(pyrazol-1-yl)pyridine; In acetic acid; dimethyl sulfoxide; at 80 ℃; for 16h;

DOI:10.1002/adsc.202100763

upstream raw materials:

bromobenzene

1-Methoxynaphthalene

8-phenylnaphthalen-1-ol

dimethyl sulfate

Refernces

• 1、 Kwak, Hayeon,Kang, Eunsu,Song, Jae Yeong,Kang, Geunhee,Joo, Jung Min. "Pd-Catalyzed Cyclization of Alkynyl Norbornene Derivatives for the Synthesis of Benzofused Heteroarenes". supporting information. p. 4883 - 4888. Retrieved 2021/09/09.