Ribavirin IMpurity E

Base Information

• Chemical Name: Ribavirin IMpurity E
• CAS No.: 58151-90-9
• Molecular Formula: C15H16N4O6
• Molecular Weight: 348.315
• Mol file: 58151-90-9.mol

Synonyms:1-(5-O-benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxaMide;5'-O-Benzoyl Ribavirin;Ribavirin IMpurity E

Chemical Property of Ribavirin IMpurity E

Chemical Property:

• Melting Point: 182 - 184 °C
• PSA: 149.79000
• LogP: -0.44650
• Storage Temp.: -20°C Freezer
• Solubility.: DMF (Slightly), DMSO (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

5’-O-BenzoylRibavirin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 5’-O-Benzoyl Ribavirin is an impurity of Ribavirin (R414475). Ribavirin impurity E.

Technology Process of Ribavirin IMpurity E

There total 2 articles about Ribavirin IMpurity E which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzoic acid (65-85-0,8013-63-6) + ribavirin (36791-04-5,66510-90-5) → ribavirin benzoate (58151-90-9)

Guidance literature:

In water;

Reference yield:

→ ribavirin benzoate (58151-90-9)

Guidance literature:

entspr. 2.3.5-O-Benzoylverb., NH3/CH3OH;

Reference yield:

ribavirin benzoate (58151-90-9) → ribavirin (36791-04-5,66510-90-5)

Guidance literature:

With pyrographite; In dichloromethane; acetonitrile; at 60 ℃; for 0.333333h;

upstream raw materials:

benzoic acid

ribavirin

Downstream raw materials:

ribavirin

Refernces

• 1、 -. "1-(β,-D-ribofuranosyl)-1,2,4-triazole acid esters". . . Retrieved 2008/06/13.