1-Methoxy-3-phenoxybenzene

Base Information

• Chemical Name: 1-Methoxy-3-phenoxybenzene
• CAS No.: 1655-68-1
• Molecular Formula: C13H12 O2
• Molecular Weight: 200.237
• Hs Code.: 2909309090
• European Community (EC) Number: 216-748-8
• NSC Number: 57097
• UNII: 1M0VG5IZH1
• DSSTox Substance ID: DTXSID7061851
• Nikkaji Number: J117.512B
• Wikidata: Q81989709
• Mol file: 1655-68-1.mol

Synonyms:1-Methoxy-3-phenoxybenzene;1655-68-1;3-Phenoxyanisole;Benzene, 1-methoxy-3-phenoxy-;m-Phenoxyanisole;m-Methoxyphenyl phenyl ether;m-Phenoxymethoxybenzene;3-Methoxyphenoxybenzene;m-Phenoxyphenol monomethyl ether;3-Methoxydiphenyl ether;EINECS 216-748-8;NSC 57097;1M0VG5IZH1;NSC-57097;UNII-1M0VG5IZH1;SCHEMBL491308;Benzene, 1-methoxy-3-phenyloxy;DTXSID7061851;NSC57097;MFCD00455605;AS-59986;LS-30859;BB 0323399;W-205945

Chemical Property of 1-Methoxy-3-phenoxybenzene

Chemical Property:

• Vapor Pressure: 0.00291mmHg at 25°C
• Refractive Index: 1.5790
• Boiling Point: 294.1°Cat760mmHg
• Flash Point: 115.7°C
• PSA: 18.46000
• Density: 1.088g/cm³
• LogP: 3.48750
• Water Solubility.: Insoluble in water.
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 200.083729621
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

99% ^*data from raw suppliers

1-METHOXY-3-PHENOXYBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC=C1)OC2=CC=CC=C2

Technology Process of 1-Methoxy-3-phenoxybenzene

There total 36 articles about 1-Methoxy-3-phenoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

O-methylresorcine (150-19-6) + iodobenzene (591-50-4) → 1-methoxy-3-phenoxybenzene (1655-68-1)

Guidance literature:

With 2,2,6,6-tetramethylheptane-3,5-dione; iron(III) chloride; caesium carbonate; In N,N-dimethyl-formamide; at 135 ℃; for 20h;

DOI:10.1002/anie.200704018

Reference yield: 99.0%

O-methylresorcine (150-19-6) + diphenyliodonium tetrafluoroborate → 1-methoxy-3-phenoxybenzene (1655-68-1)

Guidance literature:

O-methylresorcine; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.25h;

diphenyliodonium tetrafluoroborate; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1021/ol200265t

Reference yield: 99.0%

diphenyliodonium tetrafluoroborate + 2-Phenylphenol (90-43-7,287950-96-3) → 1-methoxy-3-phenoxybenzene (1655-68-1)

Guidance literature:

2-Phenylphenol; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.25h;

diphenyliodonium tetrafluoroborate; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1002/chem.201201645

upstream raw materials:

O-methylresorcine

bromobenzene

3-methoxyphenyl bromide

phenol

Downstream raw materials:

O-methylresorcine

(2,4-dinitro-phenyl)-(4-methoxy-2-phenoxy-phenyl)-diazene

4-(2,4-dinitro-phenylazo)-3-methoxy-phenol

meta-phenoxyphenol

Refernces

• 1、 Oliveira, Ana M. A. G.,Raposo, M. Manuela M.,Oliveira-Campos, Ana M. F.,Griffiths, John,Machado, Antonio E. H.. "Synthesis of psoralen analogues based on dibenzofuran". . p. 2900 - 2907. Retrieved 2003.
• 2、 -. "Compound and light emitting device comprising the same". Paragraph 0398-0401. . Retrieved 2021/09/14.