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Amphetamine

Base Information Edit
  • Chemical Name:Amphetamine
  • CAS No.:300-62-9
  • Deprecated CAS:17108-96-2,60-15-1,96332-84-2,60-15-1,96332-84-2
  • Molecular Formula:C9H13N
  • Molecular Weight:135.209
  • Hs Code.:
  • European Community (EC) Number:206-096-2,200-458-3
  • NSC Number:73713,27159
  • UN Number:2811
  • UNII:CK833KGX7E
  • DSSTox Substance ID:DTXSID4022600
  • Nikkaji Number:J28.384C
  • Wikipedia:Amphetamine
  • Wikidata:Q179452
  • NCI Thesaurus Code:C62006
  • RXCUI:725
  • Pharos Ligand ID:HCAJ4FW3L8M5
  • Metabolomics Workbench ID:133784
  • ChEMBL ID:CHEMBL405
  • Mol file:300-62-9.mol
Amphetamine

Synonyms:Amfetamine;Amphetamine;Amphetamine Sulfate;Amphetamine Sulfate (2:1);Centramina;Desoxynorephedrin;Fenamine;l Amphetamine;l-Amphetamine;levo Amphetamine;levo-Amphetamine;Levoamphetamine;Mydrial;Phenamine;Phenopromin;Sulfate, Amphetamine;Thyramine

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Amphetamine Edit
Chemical Property:
  • Vapor Pressure:0.307mmHg at 25°C 
  • Melting Point:146 °C 
  • Refractive Index:1.527 
  • Boiling Point:201.5 °C at 760 mmHg 
  • PKA:9.94±0.10(Predicted) 
  • Flash Point:87.4 °C 
  • PSA:26.02000 
  • Density:0.946 g/cm3 
  • LogP:2.27660 
  • Storage Temp.:?20°C 
  • XLogP3:1.8
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:1
  • Rotatable Bond Count:2
  • Exact Mass:135.104799419
  • Heavy Atom Count:10
  • Complexity:84.7
  • Transport DOT Label:Poison
Purity/Quality:
Safty Information:
  • Pictogram(s): F,T 
  • Hazard Codes:F,T 
  • Statements: 11-23/24/25-39/23/24/25 
  • Safety Statements: 16-36/37-45-7 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CC(CC1=CC=CC=C1)N
  • Recent ClinicalTrials:Imaging Extrastriatal Dopamine Release in Tobacco Smokers and Nonsmokers
  • Uses Amphetamine is the basis of a group of hallucinogenic, habit-forming drugs that affect the central nervous system. The drug also finds medical application, notably in appetite suppressants. It should be emphasized that administration of amphetamines for prolonged periods in connection with weight-reduction programs may lead to drug dependence. Professionals must pay particular attention to the possibility of persons obtaining amphetamines for nontherapeutic use or distribution to others. Amphetamines are advocated for use in a wide variety of conditions but are medically approved for the treatment of attention-deficit hyperactivity disorder, narcolepsy, and weight loss. Amphetamines are also popular drugs of abuse available in several forms for different routes of abuse. Stimulant (central).
Technology Process of Amphetamine

There total 95 articles about Amphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 5% Pd(II)/C(eggshell); hydrogen; In tetrahydrofuran; at 20 ℃; for 3h; under 1 Torr;
DOI:10.1080/00397910903097302
Guidance literature:
With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 16h; under 760.051 Torr; Inert atmosphere;
Guidance literature:
With sodium tetrahydroborate; borane-THF; In tetrahydrofuran; at 25 ℃; for 144h;
DOI:10.1016/S0040-4020(01)89059-1