BENZENESULFONYLAMINO-ACETIC ACID

Base Information

• Chemical Name: BENZENESULFONYLAMINO-ACETIC ACID
• CAS No.: 5398-96-9
• Molecular Formula: C8H9NO4S
• Molecular Weight: 215.23
• Hs Code.: 2935009090
• Mol file: 5398-96-9.mol

Synonyms:N-benzenesulfonyl-glycine;2-(phenylsulfonamido)acetic acid;N-Phenylsulfonylglycine;phenylsulfonylaminoacetic acid;N-benzenesulphonylglycine;

Chemical Property of BENZENESULFONYLAMINO-ACETIC ACID

Chemical Property:

• Vapor Pressure: 4.75E-08mmHg at 25°C
• Boiling Point: 426.9°Cat760mmHg
• Flash Point: 212°C
• PSA: 91.85000
• Density: 1.423g/cm³
• LogP: 1.52120

Purity/Quality:

99%min ^*data from raw suppliers

2-benzenesulfonamidoaceticAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

Useful:

Technology Process of BENZENESULFONYLAMINO-ACETIC ACID

There total 13 articles about BENZENESULFONYLAMINO-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.61%

benzenesulfonyl chloride (98-09-9) + glycine (56-40-6,18875-39-3,25718-94-9) → N-phenylsulfonylglycine (5398-96-9)

Guidance literature:

With sodium carbonate; In water; for 5h;

DOI:10.1016/j.ejmech.2017.04.029

Reference yield: 43.0%

Iodoacetic acid (64-69-7) + N-(phenylsulfonyl)acetamide (5661-14-3) → N-phenylsulfonylglycine (5398-96-9)

Guidance literature:

at 25 ℃; for 8h; pH=8; aq. buffer;

DOI:10.1016/j.bmcl.2010.01.164

Reference yield:

C8H8N2O6S (86674-20-6) → glycolic Acid (79-14-1) + N-phenylsulfonylglycine (5398-96-9) + benzenesulfonic acid (98-11-3)

Guidance literature:

With sulfuric acid; In water; at 25 ℃; Rate constant;

upstream raw materials:

benzenesulfonamide

sodium monochloroacetic acid

chloroacetic acid

benzenesulfonyl chloride

Downstream raw materials:

N-Phenylsulfonylglycine methyl ester

N-benzenesulfonyl-N-phenyl-glycine

N-benzenesulfonyl-N-isobutyl-glycine

1-(phenylsulphonylamino)acetyl chloride

Refernces

• 1、 Bongo, Nlandu B.,Tomohiro, Takenori,Hatanaka, Yasumaru. "Efficient approach for profiling photoaffinity labeled peptides with a cleavable biotinyl photoprobe". . p. 1834 - 1836. Retrieved 2010.
• 2、 Ugwu, David Izuchukwu,Okoro, Uchechukwu Chris,Mishra, Narendra Kumar. "Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety". . . Retrieved 2018/01/17.
• 3、 Ugwu, David I.,Okoro, Uchechukwu C.,Mishra, Narendra K.,Okafor, Sunday N.. "Novel Phenoxazinones as potent agonist of PPAR-α: Design, synthesis, molecular docking and in vivo studies". . . Retrieved 2018/05/30.