methyl bis(2-hydroxyphenyl)phosphinate

Base Information

• Chemical Name: methyl bis(2-hydroxyphenyl)phosphinate
• CAS No.: 1075702-09-8
• Molecular Formula: C₁₃H₁₃O₄P
• Molecular Weight: 264.218
• Mol file: 1075702-09-8.mol

Synonyms:methyl bis(2-hydroxyphenyl)phosphinate

Chemical Property of methyl bis(2-hydroxyphenyl)phosphinate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of methyl bis(2-hydroxyphenyl)phosphinate

There total 1 articles about methyl bis(2-hydroxyphenyl)phosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

phosphoric acid methyl ester diphenyl ester (115-89-9) → methyl bis(2-hydroxyphenyl)phosphinate (1075702-09-8)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -75 - 20 ℃;

DOI:10.1016/j.tet.2008.07.111

Reference yield: 96.0%

methyl bis(2-hydroxyphenyl)phosphinate (1075702-09-8) + benzyl 2-(((tert-butoxycarbonyl)oxy)methyl)acrylate (1588998-81-5) → C24H23O6P

Guidance literature:

With 4-((3R,5R,6S,7S)-3-Ethyl-4-oxa-1-aza-tricyclo[4.3.1.0^3,7]dec-5-yl)-quinolin-6-ol; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1039/C8SC05439H

Reference yield: 88.0%

methyl bis(2-hydroxyphenyl)phosphinate (1075702-09-8) + 1-naphthaldehyde (66-77-3) → (R)-2-((2-hydroxyphenyl)(methoxy)phosphoryl)phenyl 1-naphthoate

Guidance literature:

With 5a(R),10b(S)-5a,10b-dihydro-2-(pentafluorophenyl)-4H,6H-indeno[2,1-b][1,2,4]triazolo[4,3-d][1,4]oxazinium tetrafluoroborate; 3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone; triethylamine; In tetrahydrofuran; at -40 ℃; for 24h; Reagent/catalyst; enantioselective reaction; Catalytic behavior; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.6b04624

upstream raw materials:

phosphoric acid methyl ester diphenyl ester

Refernces