4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate

Base Information

• Chemical Name: 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate
• CAS No.: 99841-22-2
• Molecular Formula: C₁₁H₁₄N₂O₂S
• Molecular Weight: 238.31
• Mol file: 99841-22-2.mol

Synonyms:4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate

Chemical Property of 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate

There total 6 articles about 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,2'-(phenylimino)bis[ethanol] (120-07-0) + ammonium thiocyanate (1147550-11-5) → 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate (99841-22-2)

Guidance literature:

2,2'-(phenylimino)bis[ethanol]; ammonium thiocyanate; With N-sulfonic acid pyridinium chloride; In ethanol; water; at 20 ℃; for 0.0833333h; Green chemistry;

With dihydrogen peroxide; In ethanol; water; at 20 ℃; for 0.5h; regioselective reaction; Green chemistry;

DOI:10.1080/17415993.2017.1422505

Reference yield: 88.0%

2,2'-(phenylimino)bis[ethanol] (120-07-0) + potassium thioacyanate (333-20-0) → 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate (99841-22-2)

Guidance literature:

With periodic acid dihydrate; In water; at 20 ℃; for 0.583333h; regioselective reaction;

DOI:10.1002/hlca.201100244

Reference yield: 87.0%

2,2'-(phenylimino)bis[ethanol] (120-07-0) → 4-[N,N-bis(2-hydroxyethyl)amino]benzenethiocyanate (99841-22-2)

Guidance literature:

2,2'-(phenylimino)bis[ethanol]; silica-supported pyridinium sulfonic acid thiocyanate; In ethanol; water; at 20 ℃; for 0.0833333h; Green chemistry;

With dihydrogen peroxide; In ethanol; water; at 20 ℃; for 0.75h; regioselective reaction; Green chemistry;

DOI:10.1080/17415993.2017.1422505

upstream raw materials:

oxirane

4-thiocyanatoaniline

2,2'-(phenylimino)bis[ethanol]

potassium thioacyanate

Downstream raw materials:

4-benzenethiol

Refernces

• 1、 Sajjadifar, Sami,Mansouri, Ghobad,Nikseresht, Ahmad,Kakaei Azani, Fatemeh. "Novel Br?nsted acidic ionic liquids catalyzed one-pot reaction of highly green regioselective thiocyanation of N-containing aromatic and heteroaromatic compounds at room temperature". . p. 294 - 307. Retrieved 2018/02/06.
• 2、 Khazaei, Ardeshir,Zolfigol, Mohammad Ali,Mokhlesi, Mohmmad,Panah, Fateme Derakhshan,Sajjadifar, Sami. "Simple and highly efficient catalytic thiocyanation of aromatic compounds in aqueous media". experimental part. p. 106 - 114. Retrieved 2012/02/14.