4-PHENYL-3,5-THIOMORPHOLINEDIONE

Base Information

• Chemical Name: 4-PHENYL-3,5-THIOMORPHOLINEDIONE
• CAS No.: 130968-47-7
• Molecular Formula: C₁₀H₉NO₂S
• Molecular Weight: 207.253
• Mol file: 130968-47-7.mol

Synonyms:4-phenyltetrahydro-1,4-thiazine-3,5-dione

Chemical Property of 4-PHENYL-3,5-THIOMORPHOLINEDIONE

Chemical Property:

Purity/Quality:

4-PHENYL-3,5-THIOMORPHOLINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-PHENYL-3,5-THIOMORPHOLINEDIONE

There total 3 articles about 4-PHENYL-3,5-THIOMORPHOLINEDIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thioglycolic acid monoanilide (70648-87-2) → 4-phenyltetrahydro-1,4-thiazine-3,5-dione (130968-47-7)

Guidance literature:

With acetyl chloride;

Reference yield:

aniline (62-53-3) → 4-phenyltetrahydro-1,4-thiazine-3,5-dione (130968-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 24 h / 20 °C

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine / tetrahydrofuran / 1 h / 20 °C / Inert atmosphere

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.molstruc.2014.08.046

Reference yield:

aniline (62-53-3) → 4-phenyltetrahydro-1,4-thiazine-3,5-dione (130968-47-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Heating

2: 1.96 g / AcCl / Heating

With acetyl chloride;

DOI:10.1023/A:1014561327169

upstream raw materials:

thioglycolic acid monoanilide

aniline

Refernces

• 1、 Aitken,Farrell,Kirton. "Synthesis and pyrolysis of tetrahydro-1,4-oxazine-3,5-diones and tetrahydro-1,4-thiazine-3,5-diones". . p. 1526 - 1531. Retrieved 2007/10/03.