(E)-2-phenyl-1-phenoxyethene

Base Information

• Chemical Name: (E)-2-phenyl-1-phenoxyethene
• CAS No.: 66694-17-5
• Molecular Formula: C₁₄H₁₂O
• Molecular Weight: 196.249
• Mol file: 66694-17-5.mol

Synonyms:(E)-2-phenyl-1-phenoxyethene

Chemical Property of (E)-2-phenyl-1-phenoxyethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-phenyl-1-phenoxyethene

There total 79 articles about (E)-2-phenyl-1-phenoxyethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

styrene oxide (96-09-3) + 2-(trimethylsilyl)phenyl trifluoromethanesulfonate (88284-48-4) → diphenylether (101-84-8) + 3-phenyl-2,3-dihydrobenzofuran (57049-58-8) + phenanthrene (85-01-8) + (E,Z)-β-phenoxystyrene (39153-68-9,66694-17-5,32546-83-1)

Guidance literature:

With cesium fluoride; In acetonitrile; at 20 ℃; for 24h; Further byproducts.;

DOI:10.1055/s-2007-977460

Reference yield:

2-phenoxy-1-phenylethanone (721-04-0) → ethylbenzene (100-41-4,27536-89-6) + (E,Z)-β-phenoxystyrene (39153-68-9,66694-17-5,32546-83-1)

Guidance literature:

Multi-step reaction with 2 steps

1: MnMoS; hydrogen / methanol / 6 h / 180 °C / 7500.75 Torr

2: nickel-molybdenum sulfide; hydrogen / acetonitrile / 4 h / 180 °C / 7500.75 Torr

With nickel-molybdenum sulfide; MnMoS; hydrogen; In methanol; acetonitrile;

DOI:10.1039/c6gc01456a

Reference yield:

α-bromoacetophenone (70-11-1) → ethylbenzene (100-41-4,27536-89-6) + (E,Z)-β-phenoxystyrene (39153-68-9,66694-17-5,32546-83-1)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide / N,N-dimethyl-formamide / 16 h / 30 °C

2: sodium tetrahydroborate / methanol / 12 h / 30 °C

3: nickel-molybdenum sulfide; hydrogen / acetonitrile / 4 h / 180 °C / 7500.75 Torr

With sodium tetrahydroborate; nickel-molybdenum sulfide; hydrogen; potassium hydroxide; In methanol; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1039/c6gc01456a

upstream raw materials:

o-(1-phenylethoxy)iodobenzene

(±)-cis-3-phenoxy-1-(p-methoxyphenyl)-4-phenyl-2-azetidinone

(±)-cis-3-phenoxy-1-(p-chlorophenyl)-4-phenyl-2-azetidinone

benzylidene phenylamine

Downstream raw materials:

phenol

ethylbenzene

styrene

β-ethoxystyrene

Refernces

• 1、 Kandasamy, Jeyakumar,Lee, Yong Rok,Singh, Adesh Kumar,Venkatesh, Rapelly. "Palladium-catalyzed synthesis of α-aryl acetophenones from styryl ethers and aryl diazonium saltsviaregioselective Heck arylation at room temperature". supporting information. p. 7832 - 7837. Retrieved 2021/09/28.
• 2、 Zhang, Chaofeng,Lu, Jianmin,Zhang, Xiaochen,Macarthur, Katherine,Heggen, Marc,Li, Hongji,Wang, Feng. "Cleavage of the lignin β-O-4 ether bond: Via a dehydroxylation-hydrogenation strategy over a NiMo sulfide catalyst". . p. 6545 - 6555. Retrieved 2018/06/06.