1-Bromo-3-tert-butylbenzene

Base Information

• Chemical Name: 1-Bromo-3-tert-butylbenzene
• CAS No.: 3972-64-3
• Molecular Formula: C10H13Br
• Molecular Weight: 213.117
• Hs Code.: 2903998090
• Mol file: 3972-64-3.mol

Synonyms:Benzene,1-bromo-3-tert-butyl- (6CI,8CI);3-tert-Butyl-1-bromobenzene;3-tert-Butylphenylbromide;m-Bromo-tert-butylbenzene;m-tert-Butylbromobenzene;

Chemical Property of 1-Bromo-3-tert-butylbenzene

Chemical Property:

• Vapor Pressure: 0.253mmHg at 25°C
• Refractive Index: 1.519
• Boiling Point: 212.4 °C at 760 mmHg
• Flash Point: 81.1 °C
• PSA: 0.00000
• Density: 1.237 g/cm³
• LogP: 3.74660
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

1-Bromo-3-tert-butylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Bromo-3-tert-butylbenzene

There total 12 articles about 1-Bromo-3-tert-butylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-bromo-4-tert-butylaniline (103273-01-4) → 1-bromo-3-(tertbutyl)benzene (3972-64-3)

Guidance literature:

2-bromo-4-tert-butylaniline; With sulfuric acid; acetic acid; sodium nitrite; In water; at 10 ℃; Cooling;

With ferrous(II) sulfate heptahydrate; In water; N,N-dimethyl-formamide;

DOI:10.1055/a-1683-0315

Reference yield: 75.0%

1,4-di-tert-butylbenzene (1012-72-2) → 1-bromo-3-(tertbutyl)benzene (3972-64-3) + 2-bromo-1,4-di-tert-butylbenzene (6683-74-5)

Guidance literature:

With molecular sieve; bromine; iron(III) chloride; In ethyl bromide; at 20 ℃; for 1h;

DOI:10.1007/BF02496413

Reference yield: 30.0%

3-tert-butylphenyol (585-34-2) → 1-bromo-3-(tertbutyl)benzene (3972-64-3)

Guidance literature:

With triphenylphosphine dibromide 1:1 addition complex; at 340 ℃;

DOI:10.1021/jo00179a033

upstream raw materials:

2-bromo-4-tert-butylaniline

2-bromo-4-tert-butyl-aniline; hydrochloride

3-tert-butylphenyol

1,4-di-tert-butylbenzene

Downstream raw materials:

3-tert-butyl-N-(4-methoxyphenyl)thiobenzamide

2-bromo-4-tert-butyl-benzenesulfonic acid amide

(2-bromo-4-tert-butyl-phenyl)-phenyl sulfone

2-benzenesulfonyl-5-tert-butyl-benzoic acid

Refernces

• 1、 John, Alexandra,Kirschner, Sven,Fengel, Melina K.,Bolte, Michael,Lerner, Hans-Wolfram,Wagner, Matthias. "Simultaneous expansion of 9,10 boron-doped anthracene in longitudinal and lateral directions". supporting information. p. 1871 - 1877. Retrieved 2019/02/28.
• 2、 Austin, Mark,Egan, Oliver J.,Tully, Raymond,Pratt, Albert C.. "Quinoline synthesis: Scope and regiochemistry of photocyclisation of substituted benzylidenecyclopentanone O-alkyl and O-acetyloximes". . p. 3778 - 3786. Retrieved 2008/10/09.