3-Amino-2-methoxydibenzofuran

Base Information

• Chemical Name: 3-Amino-2-methoxydibenzofuran
• CAS No.: 5834-17-3
• Molecular Formula: C13H11 N O2
• Molecular Weight: 213.236
• Hs Code.: 2932990090
• UNII: 36C8S7H3NZ
• DSSTox Substance ID: DTXSID9020825
• Nikkaji Number: J34.843K
• Wikidata: Q27256551
• ChEMBL ID: CHEMBL3188571
• Mol file: 5834-17-3.mol

Synonyms:3-Amino-2-methoxydibenzofuran;5834-17-3;2-Methoxydibenzo[b,d]furan-3-amine;2-Methoxy-3-aminodibenzofuran;(2-methoxydibenzo[b,d]furan-3-yl)amine;2-methoxydibenzofuran-3-amine;2-Methoxy-3-dibenzofuranamine;BRN 0176944;3-DIBENZOFURANAMINE, 2-METHOXY-;2-Amino-3-methoxydiphenylenoxyd;UNII-36C8S7H3NZ;2-Amino-3-methoxydiphenylenoxyd [German];36C8S7H3NZ;DTXSID9020825;2-(methyloxy)dibenzo[b,d]furan-3-amine;4-18-00-07352 (Beilstein Handbook Reference);2-methoxydibenzo[b,d]furan-3-ylamine;Oprea1_315231;SCHEMBL92042;DTXCID70825;3-Amino-2-methoxy-dibenzofuran;CHEMBL3188571;3-amino-2-methoxydibenzo[b]furan;STR05048;3-Amino-2-methoxydibenzo[b,d]furan;Tox21_200262;BBL027784;MFCD00011554;STK400206;3-Amino-2-methoxydibenzofuran, 97%;AKOS000119461;2-Methoxydibenzo[b,d]furan-3-amine #;CCG-274808;LS-7494;METHOXY-3-AMINODIBENZOFURAN, 2-;NCGC00248582-01;NCGC00257816-01;CAS-5834-17-3;CS-0204352;FT-0635873;EN300-20521;E85366;A831840;SR-01000107582;SR-01000107582-1;Q27256551;F0919-0335;Z104478554;4-methoxy-8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,5,10,12-hexaen-5-amine;4-METHOXY-8-OXATRICYCLO[7.4.0.0(2),?]TRIDECA-1(9),2(7),3,5,10,12-HEXAEN-5-AMINE

Chemical Property of 3-Amino-2-methoxydibenzofuran

Chemical Property:

• Vapor Pressure: 2.54E-06mmHg at 25°C
• Melting Point: 92-94 °C(lit.)
• Refractive Index: 1.5700 (estimate)
• Boiling Point: 391°C at 760 mmHg
• PKA: 3.91±0.30(Predicted)
• Flash Point: 190.3°C
• Density: 1.278g/cm³
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 213.078978594
• Heavy Atom Count: 16
• Complexity: 258

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-2-methoxydibenzofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C2C(=C1)C3=CC=CC=C3O2)N
• Uses: 3-Amino-2-methoxydibenzofuran has been used in the preparation of end functional poly(N-isopropylacrylamide) (PNIPAM).

Technology Process of 3-Amino-2-methoxydibenzofuran

There total 4 articles about 3-Amino-2-methoxydibenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-3-nitro-dibenzofuran (96460-88-7) → 3-amino-2-methoxydibenzofuran (5834-17-3)

Guidance literature:

With ethanol; nickel; Hydrogenation_.unter Druck;

Reference yield:

2-methoxydibenzofuran (20357-70-4) → 3-amino-2-methoxydibenzofuran (5834-17-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous nitric acid; acetic acid

2: aqueous hydrochloric acid; tin (II)-chloride

With hydrogenchloride; nitric acid; acetic acid; tin(ll) chloride;

DOI:10.1021/ja01208a014

Reference yield:

2-hydroxydibenzofuran (86-77-1) → 3-amino-2-methoxydibenzofuran (5834-17-3)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous alkaline solution

2: aqueous nitric acid; chlorobenzene

3: Raney nickel; ethanol / Hydrogenation_.unter Druck

With ethanol; alkaline solution; nitric acid; nickel; chlorobenzene;

upstream raw materials:

2-methoxy-3-nitro-dibenzofuran

2-hydroxydibenzofuran

2-methoxydibenzofuran

2-(2'-chlorophenyl)-1,4-hydroquinone

Downstream raw materials:

C₂₄H₁₅F₄NO₅