Benzylhydrazine

Base Information

• Chemical Name: Benzylhydrazine
• CAS No.: 555-96-4
• Molecular Formula: C7H10N2
• Molecular Weight: 122.17
• Hs Code.: 2928000090
• European Community (EC) Number: 611-286-7
• UNII: 9VP7PK6UMV
• DSSTox Substance ID: DTXSID2043749
• Nikkaji Number: J37.761I
• Wikidata: Q27273287
• ChEMBL ID: CHEMBL1231544
• Mol file: 555-96-4.mol

Synonyms:benzylhydrazine;benzylhydrazine dihydrochloride;benzylhydrazine monohydrochloride

Chemical Property of Benzylhydrazine

Chemical Property:

• Melting Point: 112 °C
• Refractive Index: 1.5040 (estimate)
• Boiling Point: 265.4 °C at 760 mmHg
• PKA: 8.45±0.70(Predicted)
• Flash Point: 132 °C
• PSA: 38.05000
• Density: 1.033 g/cm³
• LogP: 1.74110
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 122.084398327
• Heavy Atom Count: 9
• Complexity: 67.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

Benzylhydrazine ^*data from reagent suppliers

Safty Information:

• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNN

Technology Process of Benzylhydrazine

There total 26 articles about Benzylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(E)-benzaldehyde hydrazone (41097-64-7) → Benzylhydrazine (555-96-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1016/0040-4039(96)00836-2

Reference yield: 82.0%

benzyl chloride (100-44-7) → Benzylhydrazine (555-96-4)

Guidance literature:

With potassium carbonate; hydrazine hydrate; In water; at 40 ℃;

DOI:10.1055/s-0034-1379974

Reference yield: 79.0%

benzaldehyde (100-52-7) → Benzylhydrazine (555-96-4)

Guidance literature:

With hydrogen; hydrazine; 10percent Pd/C; In methanol; at 20 ℃;

DOI:10.1021/jo026280d

upstream raw materials:

benzaldehyde, hydrazone

benzaldehyde

benzyl chloride

N,N-dibenzylhydrazine

Downstream raw materials:

3-benzyl-carbazic acid-(2-hydroxy-ethyl ester)

isocarboxazid

2-benzyl-2,3-dihydrophthalazine-1,4-dione

2-benzyl-5-methyl-1,2-dihydro-pyrazol-3-one

Refernces

• 1、 Hosseini-Sarvari, Mona,Koohgard, Mehdi. "Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine". supporting information. p. 5905 - 5911. Retrieved 2021/07/12.
• 2、 Sharma, Swagat,Kozek, Krystian A.,Abney, Kristopher K.,Kumar, Sushil,Gautam, Nagsen,Alnouti, Yazen,David Weaver,Hopkins, Corey R.. "Discovery, synthesis and characterization of a series of (1-alkyl-3-methyl-1H-pyrazol-5-yl)-2-(5-aryl-2H-tetrazol-2-yl)acetamides as novel GIRK1/2 potassium channel activators". . p. 791 - 796. Retrieved 2019/02/06.