4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER

Base Information

• Chemical Name: 4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER
• CAS No.: 7504-67-8
• Molecular Formula: C₁₃H₁₆O₅
• Molecular Weight: 252.267
• Hs Code.: 2918199090
• Mol file: 7504-67-8.mol

Synonyms:4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER;4-Hydroxy-5-methyl-isophthalsaeure-diaethylester;Diethyl 4-hydroxy-5-methylisophthalate;

Chemical Property of 4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER

Chemical Property:

• Vapor Pressure: 1.48E-05mmHg at 25°C
• Boiling Point: 355.9°Cat760mmHg
• Flash Point: 129.3°C
• PSA: 72.83000
• Density: 1.184g/cm³
• LogP: 2.05400

Purity/Quality:

98% ^*data from raw suppliers

Diethyl4-hydroxy-5-methylisophthalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER

There total 4 articles about 4-HYDROXY-5-METHYL-ISOPHTHALIC ACID DIETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 3-ethoxyacrylate (1001-26-9) + Diethyl methylmalonate (609-08-5) → 4-hydroxy-5-methyl-isophthalic acid diethyl ester (7504-67-8)

Guidance literature:

With diethyl ether; sodium ethanolate;

DOI:10.1021/ja01158a084

Reference yield:

ethanol (64-17-5) + 4-hydroxy-5-methyl-isophthalic acid (4365-31-5) → 4-hydroxy-5-methyl-isophthalic acid diethyl ester (7504-67-8) + 4-hydroxy-5-methyl-isophthalic acid monoethyl ester

Guidance literature:

With hydrogenchloride;

Reference yield:

ethanol (64-17-5) → 4-hydroxy-5-methyl-isophthalic acid diethyl ester (7504-67-8)

Guidance literature:

upstream raw materials:

ethanol

4-hydroxy-5-methyl-isophthalic acid

diethyl ether

ethyl 3-ethoxyacrylate

Downstream raw materials:

4-hydroxy-5-methyl-isophthalic acid