C₁₉H₂₁N₃O₄

Base Information

• Chemical Name: C₁₉H₂₁N₃O₄
• CAS No.: 881204-74-6
• Molecular Formula: C₁₉H₂₁N₃O₄
• Molecular Weight: 355.393
• Mol file: 881204-74-6.mol

Synonyms:C₁₉H₂₁N₃O₄

Chemical Property of C₁₉H₂₁N₃O₄

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₉H₂₁N₃O₄

There total 2 articles about C₁₉H₂₁N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2-ethoxy-1-iodo-4-nitrobenzene + 2-(6-methoxy-1H-indol-3-yl)ethanamine (3610-36-4) → C19H21N3O4 (881204-74-6)

Guidance literature:

With sodium t-butanolate; 1,1'-bis-(diphenylphosphino)ferrocene; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In tetrahydrofuran; at 100 - 120 ℃; for 4.5h; Product distribution / selectivity;

Reference yield: 22.0%

2-ethoxy-4-nitroanisole (36160-52-8) + 2-(6-methoxy-1H-indol-3-yl)ethanamine (3610-36-4) → C19H21N3O4 (881204-74-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; at 210 ℃; for 5h; Product distribution / selectivity;

Reference yield: 98.0%

C19H21N3O4 (881204-74-6) → C19H23N3O2

Guidance literature:

With hydrogen; Raney nickel; In tetrahydrofuran; ethanol; at 20 ℃; for 24h; under 760.051 Torr; Product distribution / selectivity;

upstream raw materials:

2-ethoxy-4-nitroanisole

2-(6-methoxy-1H-indol-3-yl)ethanamine

Refernces