1-Deoxy-1-morpholinofructose

Base Information

• Chemical Name: 1-Deoxy-1-morpholinofructose
• CAS No.: 6291-16-3
• Molecular Formula: C10H19 N O6
• Molecular Weight: 249.264
• Hs Code.: 29349990
• DSSTox Substance ID: DTXSID50978700
• Mol file: 6291-16-3.mol

Synonyms:1-deoxy-1-morpholinofructose;1-DMF

Chemical Property of 1-Deoxy-1-morpholinofructose

Chemical Property:

• Vapor Pressure: 6.61E-17mmHg at 25°C
• Melting Point: 147-150 °C
• Boiling Point: 600.1oC at760mmHg
• PKA: 12.06±0.20(Predicted)
• Flash Point: 316.8oC
• PSA: 110.46000
• Density: 1.507g/cm3
• LogP: -3.09940
• Storage Temp.: −20°C
• Solubility.: pyridine: 50 mg/mL, clear, faintly yellow
• XLogP3: -3.4
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 265.11615195
• Heavy Atom Count: 18
• Complexity: 269

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Deoxy-1-morpholino-D-fructose ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1COCCN1C(C(=O)C(C(C(CO)O)O)O)O
• Isomeric SMILES: C1COCCN1C(C(=O)[C@H]([C@@H]([C@@H](CO)O)O)O)O
• Uses: DMF (1-Deoxy-1-morpholino-D-fructose), an analog of the 1-desoxy-1-amino-fructose radical found in glycated proteins, is used in the development of glycation assays.

Technology Process of 1-Deoxy-1-morpholinofructose

There total 3 articles about 1-Deoxy-1-morpholinofructose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + D-glucose (50-99-7) → 1-deoxy-1-morpholino-D-fructose (6291-16-3)

Guidance literature:

With ethanol; weiteres Edukt: Malonsaeure-diaethylester;

DOI:10.1021/ja01098a019

Reference yield:

morpholine (110-91-8,99108-56-2) + D-Mannose (3458-28-4) → 1-deoxy-1-morpholino-D-fructose (6291-16-3)

Guidance literature:

With ethanol; weiteres Edukt: Malonsaeure-diaethylester;

DOI:10.1021/ja01098a019

Reference yield:

→ 1-deoxy-1-morpholino-D-fructose (6291-16-3)

Guidance literature:

D-Glucose, Morpholin, versch. Thiole (bes.Thiophenol) als Kat.;

upstream raw materials:

morpholine

D-Mannose

D-glucose

Downstream raw materials:

morpholine

D-Mannose

D-glucose

4-morpholinecarboxaldehyde