3-(2,5-dimethoxyphenyl)propanoylhydrazine

Base Information

• Chemical Name: 3-(2,5-dimethoxyphenyl)propanoylhydrazine
• CAS No.: 436155-33-8
• Molecular Formula: C₁₁H₁₆N₂O₃
• Molecular Weight: 224.26
• Mol file: 436155-33-8.mol

Synonyms:3-(2,5-dimethoxyphenyl)propanoylhydrazine

Chemical Property of 3-(2,5-dimethoxyphenyl)propanoylhydrazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2,5-dimethoxyphenyl)propanoylhydrazine

There total 4 articles about 3-(2,5-dimethoxyphenyl)propanoylhydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl 3-(2,5-dimethoxyphenyl)propionate (62397-61-9) → 3-(2,5-dimethoxyphenyl)propanoylhydrazine (436155-33-8)

Guidance literature:

With hydrazine hydrate; at 110 - 120 ℃;

DOI:10.1039/b110414d

Reference yield:

ethyl E-3-(2,5-dimethoxyphenyl)propanoate (72018-06-5) → 3-(2,5-dimethoxyphenyl)propanoylhydrazine (436155-33-8)

Guidance literature:

With pentan-1-ol; hydrazine hydrate;

DOI:10.1007/s002390010095

Reference yield:

3-(2,5-dimethoxyphenyl)propanoic acid (10538-49-5) → 3-(2,5-dimethoxyphenyl)propanoylhydrazine (436155-33-8)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene; sulfuric acid / unter Entfernen des entstehenden Wassers

2: amyl alcohol; hydrazine hydrate

With pentan-1-ol; sulfuric acid; hydrazine hydrate; benzene;

DOI:10.1007/s002390010095

upstream raw materials:

ethyl E-3-(2,5-dimethoxyphenyl)propanoate

methyl 3-(2,5-dimethoxyphenyl)propionate

3-(2,5-dimethoxyphenyl)propanoic acid

trans-2,5-dimethoxycinnamic acid

Downstream raw materials:

2,5-dihydroxyphenylethylamine

phenyl (6-hydroxy-7-methoxy-2-oxo-1,2,3,4-tetrahydroquinolin-1-yl)carbamate

phenyl 2-[3-(2,5-dimethoxyphenyl)propanoyl]hydrazinecarboxylate

2,5-dimethoxyphenethylamine

Refernces