N-Benzyl-N,N'-dimethylethylenediamine

Base Information

• Chemical Name: N-Benzyl-N,N'-dimethylethylenediamine
• CAS No.: 102-11-4
• Molecular Formula: C11H18 N2
• Molecular Weight: 178.277
• Hs Code.: 2921590090
• European Community (EC) Number: 203-006-3
• NSC Number: 166313
• UNII: H725296YU4
• DSSTox Substance ID: DTXSID0059245
• Nikkaji Number: J182.149K
• Wikidata: Q81988706
• Mol file: 102-11-4.mol

Synonyms:N-Benzyl-N,N'-dimethylethylenediamine;102-11-4;N1-benzyl-N1,N2-dimethylethane-1,2-diamine;N'-benzyl-N,N'-dimethylethane-1,2-diamine;1,2-Ethanediamine, N,N'-dimethyl-N-(phenylmethyl)-;1,2-Ethanediamine, N1,N2-dimethyl-N1-(phenylmethyl)-;Benzyl(methyl)(2-methylaminoethyl)amine;EINECS 203-006-3;H725296YU4;NSC 166313;NSC-166313;Ethylenediamine, N-benzyl-N,N'-dimethyl-;N-benzyl-N,N'-dimethylethane-1,2-diamine;N-BENZYL-N N/'-DIMETHYLETHYLENEDIAMINE;benzyl(methyl)[2-(methylamino)ethyl]amine;BENZYL(METHYL)(2-(METHYLAMINO)ETHYL)AMINE;N-benzyl-N-methyl-N'-methylethylenediamine;NSC166313;C(N(C)CCNC)c1ccccc1;Ethylenediamine,N'-dimethyl-;SCHEMBL1268109;DTXSID0059245;UNII-H725296YU4;n-benzyl-n,n-dimethylethylenediamine;MFCD00014856;ZB1743;1, N,N'-dimethyl-N-(phenylmethyl)-;AKOS000257041;benzyl(methyl)(2-methylaminoethyl)amin;N,N'-Dimethyl-N-benzylethylenediamine;N-Benzyl-N, N'-dimethylethylenediamine;N-benzyl-N,N'-dimethyl-ethylenediamine;N-benzyl-N,N'-dimethylethylene-diamine;N-Benzyl-N,N/'-dimethylethylenediamine;AM807270;BS-19148;N-BENZYL-NN-DIMETHYLETHYLENEDIAMINE;B3246;CS-0205106;FT-0651064;N-Benzyl-N,N'-dimethyl-ethane-1,2-diamine;methyl 2-[methyl(phenylmethyl)amino]ethylamine;EN300-6978991;methyl 2-[methyl (phenylmethyl)-amino]ethylamine;N1,N2-DIMETHYL-N1-(PHENYLMETHYL)-1,2-ETHANEDIAMINE;N(1)-Benzyl-N(1),N(2)-dimethyl-1,2-ethanediamine, AldrichCPR

Chemical Property of N-Benzyl-N,N'-dimethylethylenediamine

Chemical Property:

• Vapor Pressure: 0.0276mmHg at 25°C
• Refractive Index: 1.5090-1.5130
• Boiling Point: 246.1°Cat760mmHg
• Flash Point: 86.4°C
• PSA: 15.27000
• Density: 0.949g/cm³
• LogP: 1.72870
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 178.146998583
• Heavy Atom Count: 13
• Complexity: 119

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Benzyl-N,N'-dimethylethylenediamine >98.0%(GC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNCCN(C)CC1=CC=CC=C1

Technology Process of N-Benzyl-N,N'-dimethylethylenediamine

There total 10 articles about N-Benzyl-N,N'-dimethylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

tert-butyl (2-(benzyl(methyl)amino)-2-oxoethyl)carbamate (179874-14-7) → N-benzyl-N-methyl-N'-methylethylenediamine (102-11-4)

Guidance literature:

tert-butyl (2-(benzyl(methyl)amino)-2-oxoethyl)carbamate; With lithium aluminium tetrahydride; In tetrahydrofuran; for 12h; Reflux; Inert atmosphere;

With water; sodium hydroxide; In tetrahydrofuran; at 0 ℃; for 2h;

DOI:10.1039/c4gc02474e

Reference yield: 85.0%

1,3-dimethyl-2-phenylimidazolidine (23229-37-0) → N-benzyl-N-methyl-N'-methylethylenediamine (102-11-4)

Guidance literature:

1,3-dimethyl-2-phenylimidazolidine; With naphthalene; lithium; In tetrahydrofuran; at -20 ℃; for 8h;

With water; In tetrahydrofuran; for 0.5h;

DOI:10.1016/j.tet.2005.01.093

Reference yield:

benzyl chloride (100-44-7) + N,N`-dimethylethylenediamine (110-70-3) → N-benzyl-N-methyl-N'-methylethylenediamine (102-11-4)

Guidance literature:

With sodium hydrogencarbonate; In ethanol; Heating;

DOI:10.1021/jm950894b

upstream raw materials:

2-(N-benzyl-N-methylamino)ethyl chloride hydrochloride

methylamine

1,3-Dimethyl-2-phenyl-imidazolinium iodid

benzyl-(2-chloro-ethyl)-methyl-amine

Downstream raw materials:

Furan-2-carboxylic acid [2-(benzyl-methyl-amino)-ethyl]-methyl-amide

N-[2-(Benzyl-methyl-amino)-ethyl]-N-methyl-benzamide

N-Benzyl-N'-{3-[2-(4-fluoro-phenyl)-[1,3]dioxolan-2-yl]-propyl}-N,N'-dimethyl-ethane-1,2-diamine

3,4,5-trimethoxybenzoic acid 3-[[2-(benzylmethylamino)ethyl]methylamino]propyl ester

Refernces

• 1、 Azzena, Ugo,Dettori, Giovanna,Pisano, Luisa,Siotto, Immacolata. "Reductive lithiation of 1,3-dimethyl-2-arylimidazolidines". . p. 3177 - 3182. Retrieved 2007/10/03.
• 2、 Salerno, Alejandra,Ceriani, Vanina,Perillo, Isabel A.. "Reduction of Substituted 1H-4,5-Dihydroimidazolium Salts". . p. 1725 - 1733. Retrieved 2007/10/02.