4-(Butylamino)phenol

Base Information

• Chemical Name: 4-(Butylamino)phenol
• CAS No.: 103-62-8
• Molecular Formula: C10H15 N O
• Molecular Weight: 165.235
• Hs Code.: 2922299090
• European Community (EC) Number: 203-129-2
• NSC Number: 404034
• UNII: Q3B4P89C5V
• DSSTox Substance ID: DTXSID3073890
• Nikkaji Number: J154.618J
• Wikidata: Q82002480
• Mol file: 103-62-8.mol

Synonyms:4-(Butylamino)phenol;103-62-8;Phenol, 4-(butylamino)-;p-(Butylamino)phenol;p-Hydroxyphenyl-n-butylamine;N-BUTYL-P-AMINOPHENOL;N-n-Butyl-p-aminophenol;Tenamene 1;4-Butylaminophenol;Phenol, p-(butylamino)-;Du Pont Gasoline Antioxidant No. 5;EINECS 203-129-2;NSC 404034;BRN 2690441;AI3-16924;NSC-404034;3-13-00-01014 (Beilstein Handbook Reference);4-n-butylaminophenol;NSC404034;p-BAP;N-Butyl-4-aminophenol;4-(Butylamino)-phenol;Phenol,4-(butylamino)-;N(CCCC)c1ccc(O)cc1;SCHEMBL39272;Q3B4P89C5V;DTXSID3073890;AKOS009932429;LS-104125;FT-0692331

Chemical Property of 4-(Butylamino)phenol

Chemical Property:

• Vapor Pressure: 0.000537mmHg at 25°C
• Melting Point: 70-71 °C
• Refractive Index: 1.5200 (estimate)
• Boiling Point: 302.9°Cat760mmHg
• PKA: 11.03±0.26(Predicted)
• Flash Point: 128.9°C
• PSA: 32.26000
• Density: 1.053g/cm³
• LogP: 2.67720
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 108

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(BUTYLAMINO)PHENOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCNC1=CC=C(C=C1)O

Technology Process of 4-(Butylamino)phenol

There total 8 articles about 4-(Butylamino)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + butyraldehyde (123-72-8) → 4-n-butylaminophenol (103-62-8)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In water; isopropyl alcohol; at 20 ℃; for 1h;

DOI:10.1021/jo701503q

Reference yield: 96.0%

4-amino-phenol (123-30-8) + butyraldehyde (123-72-8) → 4-n-butylaminophenol (103-62-8)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In water; isopropyl alcohol; at 20 ℃; for 1h;

DOI:10.1021/jo701503q

Reference yield: 73.0%

4-amino-phenol (123-30-8) + N-butylamine (109-73-9,85404-21-3) → 4-n-butylaminophenol (103-62-8)

Guidance literature:

With palladium on activated charcoal; In tetrahydrofuran; at 170 ℃; for 1.5h; Microwave irradiation;

DOI:10.1055/s-0033-1339667

upstream raw materials:

4-amino-phenol

butyraldehyde

4-nitro-phenol

N-butylamine

Downstream raw materials:

4-(Butyl-methyl-amino)-phenol

4-N,N-dibutylaminophenol

Refernces

• 1、 Linciano, Pasquale,Pizzetti, Marianna,Porcheddu, Andrea,Taddei, Maurizio. "Use of primary amines for the selective n-alkylation of anilines by a reusable heterogeneous catalyst". . p. 2249 - 2254. Retrieved 2013/11/06.
• 2、 -. "2-Propanol derivatives as corrosion inhibitors". . . Retrieved 2008/06/13.