CID 9886567

Base Information

• Chemical Name: CID 9886567
• CAS No.: 34642-77-8
• Molecular Formula: C16H18N3NaO5S
• Molecular Weight: 387.392
• Hs Code.: 2941109900
• European Community (EC) Number: 252-124-1
• NCI Thesaurus Code: C72700
• RXCUI: 267360
• Mol file: 34642-77-8.mol

Synonyms:Actimoxi;Amoxicillin;Amoxicillin Anhydrous;Amoxicillin monopotassium salt;Amoxicillin monosodium salt;Amoxicillin Sodium;Amoxicillin trihydrate;Amoxicillin, (R*)-isomer;Amoxicilline;Amoxil;Amoxycillin;BRL 2333;BRL-2333;BRL2333;Clamoxyl;Clamoxyl G.A.;Clamoxyl parenteral;Hydroxyampicillin;Penamox;Polymox;Trimox;Wymox

Chemical Property of CID 9886567

Chemical Property:

• Appearance/Colour: A White CRYSTALLINE powder
• Melting Point: 130℃
• Boiling Point: 743.2 °C at 760 mmHg
• Flash Point: 403.3 °C
• PSA: 161.09000
• LogP: -0.28190
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: Very soluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in acetone.
• Water Solubility.: Soluble in water.
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 388.09431117
• Heavy Atom Count: 26
• Complexity: 590

Purity/Quality:

99%, ^*data from raw suppliers

Amoxicillinsodium(Amox) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=C(C=C3)O)N)C(=O)O)C.[Na]
• Isomeric SMILES: CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=C(C=C3)O)N)C(=O)O)C.[Na]
• Recent EU Clinical Trials: Efficacy and safety of different antimicrobial DURATions for the treatment of infections associated with Osteosynthesis
• Uses: Antibiotic[Note—Amoxicillin sodium will be used in combination with clavulanate potassium and marketed as ‘‘Augmentin for intravenous administration’’].

Technology Process of CID 9886567

There total 1 articles about CID 9886567 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

amoxicillin (26787-78-0,81030-75-3) → Acuotricina (34642-77-8)

Guidance literature:

amoxicillin; With triethylamine; In methanol; acetic acid methyl ester; at 0 - 5 ℃;

With sodium 2-ethylhexanoic acid; In methanol; acetic acid methyl ester; at 0 - 5 ℃; Product distribution / selectivity;

Reference yield:

Acuotricina (34642-77-8) → diketopiperazine + amoxicillin (26787-78-0,81030-75-3)

Guidance literature:

With 1,4-dithio-L-threitol; In water; at 20 ℃; Reagent/catalyst; Solvent; Temperature; Catalytic behavior; Inert atmosphere;

DOI:10.3389/fphar.2020.00189

upstream raw materials:

amoxicillin

Downstream raw materials:

amoxicillin

Refernces

• 1、 -. "PROCESS FOR PREPARING GRANULATES COMPRISING AMOXICILLIN". Page/Page column 9. . Retrieved 2008/06/13.