Bis(2-dimethylaminoethyl) ether

Base Information

• Chemical Name: Bis(2-dimethylaminoethyl) ether
• CAS No.: 3033-62-3
• Deprecated CAS: 112326-78-0,59948-21-9,357920-72-0,1021182-97-7,1379526-05-2,1615224-28-6,2570310-54-0,1021182-97-7,357920-72-0
• Molecular Formula: C8H20N2O
• Molecular Weight: 160.26
• Hs Code.: 29221990
• European Community (EC) Number: 221-220-5
• NSC Number: 109887
• UN Number: 2927
• UNII: NL66Q36V7L
• DSSTox Substance ID: DTXSID5027512
• Nikkaji Number: J12.980A
• Wikidata: Q20965408
• ChEMBL ID: CHEMBL1899933
• Mol file: 3033-62-3.mol

Synonyms:Ethylamine,2,2'-oxybis[N,N-dimethyl- (6CI,7CI,8CI);1,5-Bis(dimethylamino)-3-oxapentane;2,2'-Oxybis[N,N-dimethylethanamine];2,2'-Oxybis[N,N-dimethylethylamine];A133;A 99 (amine);BL 19;Bis(dimethylaminoethyl) ether;Bis[2-(dimethylamino)ethyl] ether;Dabco BL 11;Dabco BL 19;Dabco BL 19I;ET33B;Jeffcat ZF 20;Jeffcat ZM 20;Kaolizer 12P;MinicoTMDA;N,N,N',N'-Tetramethyl-2,2'-oxybis[ethylamine];N,N,N',N'-Tetramethyl-3-oxapentane-1,5-diamine;N,N,N',N'-Tetramethylbisaminoethyl ether;NP 99;NSC 109887;Niax A 1;Niax A99;PC CAT NP 90;Texacat ZF 20;Toyocat ETS;ZF 20;Ethanamine,2,2'-oxybis[N,N-dimethyl-;

Chemical Property of Bis(2-dimethylaminoethyl) ether

Chemical Property:

• Appearance/Colour: A clear or yellow liquid
• Vapor Pressure: 49Pa at 20℃
• Refractive Index: n 20/D 1.430
• Boiling Point: 194.8 °C at 760 mmHg
• PKA: 9.12±0.28(Predicted)
• Flash Point: 46.2 °C
• PSA: 15.71000
• Density: 0.883 g/cm³
• LogP: 0.12620
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: Soluble in water
• Water Solubility.: 100g/L at 20℃
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 160.157563266
• Heavy Atom Count: 11
• Complexity: 74.2
• Transport DOT Label: Poison Corrosive

Purity/Quality:

99.9% ^*data from raw suppliers

Bis(2-dimethylaminoethyl) Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 20-22-24-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: CN(C)CCOCCN(C)C
• Uses: Bis(2-dimethylaminoethyl) ether is an efficient tertiary amine catalyst, which is suitable for the production of almost all foam products, mainly for the production of flexible foam products, especially for high resilience and RIM products. It is characterized by high catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formulation, and the physical and chemical properties of products produced with it, such as resilience and elongation, are better than other products.

Technology Process of Bis(2-dimethylaminoethyl) ether

There total 18 articles about Bis(2-dimethylaminoethyl) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.4%

2-(N,N-dimethylamino)ethanol (108-01-0) + dimethyl amine (124-40-3) + acetylene (74-86-2,25067-58-7) → Bis<2-(N,N-dimethylamino)aethyl>aether (3033-62-3)

Guidance literature:

With potassium hydroxide; In dibutyl ether; at 100 ℃; for 5h;

Reference yield: 78.5%

2-(N,N-dimethylamino)ethanol (108-01-0) → Bis<2-(N,N-dimethylamino)aethyl>aether (3033-62-3)

Guidance literature:

In water; at 175 - 180 ℃; for 3h; Temperature; Time;

Reference yield: 76.4%

2-(N,N-dimethylamino)ethanol (108-01-0) + N-Methyldiethanolamine (105-59-9) → 2-((2-(2-(dimethylamino)ethoxy)ethyl)methyl-amino)-ethanol (83016-70-0) + Bis<2-(N,N-dimethylamino)aethyl>aether (3033-62-3)

Guidance literature:

With 4-methyl-morpholine; silica-alumina; at 145 - 155 ℃; for 15h; Reagent/catalyst; Time; Concentration; Temperature; Overall yield = 95.6 %; Catalytic behavior; Autoclave; Inert atmosphere; Sealed tube;

upstream raw materials:

dimethyl amine

3-oxa-1,5-dichloropentane

benzene

sodium N,N-dimethylethanolamine

Downstream raw materials:

formaldehyd

N,N-dimethyl-formamide

hexa-N-methyl-N,N'-(3-oxa-pentanediyl)-di-ammonium; diiodide

N,N'-dibenzyl-N,N,N',N'-tetramethyl-N,N'-(3-oxa-pentanediyl)-di-ammonium; dichloride

Refernces

• 1、 -. "Cyclic preparation method of dimethylamino ethyl ether". Paragraph 0030; 0035-0055. . Retrieved 2020/12/30.
• 2、 -. "Production method of BDMAEE". Paragraph 0065-0068; 0077-0111. . Retrieved 2019/08/01.