mixed anhydride of acetic and trichloroacetic acids

Base Information

• Chemical Name: mixed anhydride of acetic and trichloroacetic acids
• CAS No.: 32676-68-9
• Molecular Formula: C₄H₃Cl₃O₃
• Molecular Weight: 205.425
• Mol file: 32676-68-9.mol

Synonyms:mixed anhydride of acetic and trichloroacetic acids

Chemical Property of mixed anhydride of acetic and trichloroacetic acids

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of mixed anhydride of acetic and trichloroacetic acids

There total 2 articles about mixed anhydride of acetic and trichloroacetic acids which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

O-acetyl S,S-dipropyl phosphorodithioite (84103-77-5) → mixed anhydride of acetic and trichloroacetic acids (32676-68-9) + dipropyl phosphorochloridodithioite (4104-04-5) + acetic anhydride (108-24-7) + trichloroacetic acid anhydride (4124-31-6)

Guidance literature:

With trifluoroacetyl chloride; for 1h; Ambient temperature;

Reference yield:

trichloroacetate d'α-styrenyle (884-08-2) → mixed anhydride of acetic and trichloroacetic acids (32676-68-9) + acetophenone (98-86-2)

Guidance literature:

With sulfuric acid; at 25 ℃; Kinetics; Mechanism;

DOI:10.1016/S0040-4039(00)87647-9

Reference yield: 82.0%

mixed anhydride of acetic and trichloroacetic acids (32676-68-9) + (E)-N-(6-hydroxy-2,2-dimethylhex-4-enyl)-4-methylbenzenesulfonamide → (E)-5,5-dimethyl-6-p-toluenesulfonamidohex-2-enyl 2,2,2-trichloroacetate

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1002/anie.201502831

upstream raw materials:

trichloroacetate d'α-styrenyle

O-acetyl S,S-dipropyl phosphorodithioite

Downstream raw materials:

1-(4-((4-nitrophenyl)thio)phenyl)ethanone

Refernces

• 1、 Montheard, Jean-Pierre,Camps, Marcel,Benzaid, Ahmed,Pascal, Jean-Louis. "REACTION DE L'ACIDE PERCHLORIQUE SUR LES PHENYLACETYLENES SUBSTITUES. MISE EN EVIDENCE D'UN MECANISME IONIQUE ET RADICALAIRE". . p. 3483 - 3486. Retrieved 2007/10/02.