Mitiglinide calcium hydrate

Base Information

• Chemical Name: Mitiglinide calcium hydrate
• CAS No.: 207844-01-7
• Molecular Formula: 2(C19H25NO3)^.Ca^.2(H2O)
• Molecular Weight: 706.93
• Hs Code.: 2942000000
• European Community (EC) Number: 691-325-2
• UNII: 9651C21W3Z
• DSSTox Substance ID: DTXSID5046728
• Wikidata: Q27271873
• NCI Thesaurus Code: C132050
• ChEMBL ID: CHEMBL1603301
• Mol file: 207844-01-7.mol

Synonyms:2-benzyl-3-(hexahydro-2-isoindolinylcarbonyl)propionate;calcium 2-benzyl-3-(cis-hexahydro-2-isoindolinylcarbonyl)propionate dihydrate;KAD 1229;KAD-1229;miti-glinide;mitiglinide;S21403

Chemical Property of Mitiglinide calcium hydrate

Chemical Property:

• Appearance/Colour: white solid
• Melting Point: 179-185 °C
• PSA: 111.68000
• LogP: 5.53020
• Storage Temp.: -20°C Freezer
• Solubility.: Methanol (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 8
• Exact Mass: 704.3349575
• Heavy Atom Count: 49
• Complexity: 411

Purity/Quality:

99% ^*data from raw suppliers

KAD-1229 calcium hydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].O.O.[Ca+2]
• Isomeric SMILES: C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)[O-].C1CC[C@H]2CN(C[C@H]2C1)C(=O)C[C@H](CC3=CC=CC=C3)C(=O)[O-].O.O.[Ca+2]
• Recent ClinicalTrials: Post-marketing Clinical Trial of KAD-1229 in Patients With Type 2 Diabetes Mellitus
• Recent NIPH Clinical Trials: Effect of oral hypoglycemic agent for postprandial hyperglycemia administered two times daily on glycemic control in patients with type 2 diabetes with Mitiglinide / Voglibose combination tablets
• Uses: KAD-1229 binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic KAD-1229 binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic.