C₄₁H₇₃NO₁₁Si₂

Base Information

• Chemical Name: C₄₁H₇₃NO₁₁Si₂
• CAS No.: 1380168-25-1
• Molecular Formula: C₄₁H₇₃NO₁₁Si₂
• Molecular Weight: 812.202
• Mol file: 1380168-25-1.mol

Synonyms:C₄₁H₇₃NO₁₁Si₂

Chemical Property of C₄₁H₇₃NO₁₁Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₁H₇₃NO₁₁Si₂

There total 4 articles about C₄₁H₇₃NO₁₁Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C69H121NO13Si3 (1334337-70-0) → C41H73NO11Si2 (1380168-25-1)

Guidance literature:

C₆₉H₁₂₁NO₁₃Si₃; With ozone; In dichloromethane; at -68 ℃;

With water; dihydrogen peroxide; In dichloromethane; at 20 ℃; for 14h;

DOI:10.1016/j.tetlet.2011.07.094

Reference yield:

C69H121NO13Si3 (1334337-70-0) → C41H73NO11Si2 (1380168-25-1) + C42H77NO13Si2

Guidance literature:

C₆₉H₁₂₁NO₁₃Si₃; With ozone; In dichloromethane; at -68 ℃;

With dihydrogen peroxide; In dichloromethane; water; at 20 ℃; for 14h;

Reference yield:

sirolimus (53123-88-9) → C41H73NO11Si2 (1380168-25-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: triethylamine / dichloromethane / 1 h / 20 °C

2.1: ozone / dichloromethane / -68 °C

2.2: 14 h / 20 °C

With ozone; triethylamine; In dichloromethane; 2.2: Baeyer-Villiger oxidation;

DOI:10.1016/j.tetlet.2011.07.094

upstream raw materials:

C₆₉H₁₂₁NO₁₃Si₃

sirolimus

Downstream raw materials:

C₃₀H₄₇NO₁₀

C₄₂H₇₅NO₁₀Si₂

C₄₇H₇₇N₇O₁₄

Refernces

• 1、 Li, Wei,Bhat, Shridhar,Liu, Jun O.. "A simple and efficient route to the FKBP-binding domain from rapamycin". experimental part. p. 5070 - 5072. Retrieved 2011/10/09.