1-(3-methylbenzyl)-3-phenylurea

Base Information

• Chemical Name: 1-(3-methylbenzyl)-3-phenylurea
• CAS No.: 35305-45-4
• Molecular Formula: C₁₅H₁₆N₂O
• Molecular Weight: 240.305
• Mol file: 35305-45-4.mol

Synonyms:1-(3-methylbenzyl)-3-phenylurea

Chemical Property of 1-(3-methylbenzyl)-3-phenylurea

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(3-methylbenzyl)-3-phenylurea

There total 3 articles about 1-(3-methylbenzyl)-3-phenylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-phenylcarbamic acid (501-82-6) + 3-methyl-benzenemethanamine (100-81-2) → 1-(3-methylbenzyl)-3-phenylurea (35305-45-4)

Guidance literature:

N-phenylcarbamic acid; 3-methyl-benzenemethanamine; In acetonitrile; for 0.166667h; under 760.051 Torr; Inert atmosphere;

With tributylphosphine; di-tert-butyl-diazodicarboxylate; In acetonitrile; under 760.051 Torr; Inert atmosphere;

DOI:10.1021/ol100259j

Reference yield:

potassium phtalimide (1074-82-4) → 1-(3-methylbenzyl)-3-phenylurea (35305-45-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 180 - 200 °C / spaltet das entstandene N-m-Tolubenzyl-phthalimid mit konz. Salzsaeure bei 180grad bis 200grad

Reference yield:

phenyl isocyanate (103-71-9) + 3-methyl-benzenemethanamine (100-81-2) → 1-(3-methylbenzyl)-3-phenylurea (35305-45-4)

Guidance literature:

upstream raw materials:

phenyl isocyanate

3-methyl-benzenemethanamine

potassium phtalimide

N-phenylcarbamic acid

Refernces