Sodium methyl sulfate

Base Information

• Chemical Name: Sodium methyl sulfate
• CAS No.: 512-42-5
• Molecular Formula: CH4O4S.Na
• Molecular Weight: 134.088
• Hs Code.: 29209090
• European Community (EC) Number: 208-142-7
• UNII: 38W76YJ3JN
• DSSTox Substance ID: DTXSID0042406
• Nikkaji Number: J23.997F
• Wikidata: Q27256825
• Mol file: 512-42-5.mol

Synonyms:methyl sulfate;methyl sulfate, ammonium salt;methyl sulfate, potassium salt;methyl sulfate, sodium salt;monomethyl sulfate;sodium methyl sulfate

Chemical Property of Sodium methyl sulfate

Chemical Property:

• Appearance/Colour: White powder
• Melting Point: 210 °C(lit.)
• PSA: 74.81000
• Density: 1.602g/cm³
• LogP: 0.17380
• Water Solubility.: Soluble
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 133.96497403
• Heavy Atom Count: 7
• Complexity: 108

Purity/Quality:

99.9% ^*data from raw suppliers

Sodium Methyl Sulfate >98.0%(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn; T
• Hazard Codes: Xn,T
• Statements: 20/22-37/38-45-36/37/38
• Safety Statements: 23-45-53-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Metals -> Organic Compounds, Metal Salts
• Canonical SMILES: COS(=O)(=O)[O-].[Na+]
• Uses: Sodium methyl sulfate is commonly employed as a methylating agent.

Technology Process of Sodium methyl sulfate

There total 5 articles about Sodium methyl sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

p-cresol (106-44-5) + dimethyl sulfate (77-78-1) → p-methylanizole (104-93-8) + sodium methyl sulfate (512-42-5)

Guidance literature:

p-cresol; With sodium hydroxide; In ethanol; at 35 ℃; for 1h; Inert atmosphere; Cooling with ice;

dimethyl sulfate; In cyclohexane; at 40 ℃; Solvent; Reflux;

Reference yield: 94.0%

→ dimethylaminomethylenemalonic ester + sodium methyl sulfate (512-42-5)

Guidance literature:

Reference yield: 61.0%

dimethyl sulfate (77-78-1) → sodium methyl sulfate (512-42-5)

Guidance literature:

With sodium hydroxide; In water; at 70 ℃; for 0.25h; Reagent/catalyst; Solvent; Temperature;

upstream raw materials:

dimethyl sulfate

sodium iodide

sodium thiocyanide

p-cresol

Downstream raw materials:

2-(methylthio)benzoic acid

methoxybenzene

2-Nitroanisole

2-methoxybenzoic acid methyl ester

Refernces

• 1、 -. "METHOD FOR PRODUCING MONOALKYL SULFATE". Paragraph 0045. . Retrieved 2017/08/30.
• 2、 Basova, Yu. G.,Ramsh, S. M.,Ginak, A. I.. "REACTIVITY AND TAUTOMERISM OF AZOLIDINES. XLIII. KINETICS OF THE METHYLATION OF 2-PHENYLIMINO-4-THIAZOLIDINONE SODIUM SALT WITH DIMETHYL SULFATE IN ACETONITRILE". . p. 1940 - 1944. Retrieved 2007/10/02.