4-METHYL-MORPHOLINEBORANE

Base Information

• Chemical Name: 4-METHYL-MORPHOLINEBORANE
• CAS No.: 15648-16-5
• Molecular Formula: C5H14 B N O
• Molecular Weight: 114.983
• Mol file: 15648-16-5.mol

Synonyms:Boron,trihydro(4-methylmorpholine-N4)-, (T-4)-; Morpholine, 4-methyl-, compd. withBH3 (7CI); Morpholine, 4-methyl-, compd. with borane (1:1) (8CI); Borane,compd. with 4-methylmorpholine (1:1); Morpholine, 4-methyl-, boron complex;4-Methylmorpholine-borane

Chemical Property of 4-METHYL-MORPHOLINEBORANE

Chemical Property:

• Melting Point: 42-45 °C(lit.)
• Flash Point: 151 °F
• PSA: 20.31000
• LogP: -1.29760

Purity/Quality:

98%,99%, ^*data from raw suppliers

Borane 4-methylmorpholine complex ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-20/21/22-36/37/38
• Safety Statements: 16-23-26-33-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Reagent for: Labeling oligosaccharides for quantitative mass spectrometryAnalysis of sugar markers associated with Bacillus anthracis spores after cultureSynthesis of sulfated red seaweed galactan derived disaccharide alditolAnalysis of sulfated galactans from red algae by reductive hydrolysis and mild methanolysis by HPLCReactant for methanolic cleavageUsed in reductive pyrolysis of carrageenan by high performance anion-exchange chromatography

Technology Process of 4-METHYL-MORPHOLINEBORANE

There total 7 articles about 4-METHYL-MORPHOLINEBORANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methyl-morpholine (109-02-4) + Trimethyl borate (121-43-7,63156-11-6) + H2SiEt2 (542-91-6) → 4-methylmorpholine - borane (1/1) (15648-16-5)

Guidance literature:

In neat (no solvent); High Pressure; pressure: 60kg/cm**2, 150-160°C, 5h;; fractionated distn.;;

Reference yield: 97.0%

4-methyl-morpholine (109-02-4) + diethylchlorosilane (1609-19-4) + Trimethyl borate (121-43-7,63156-11-6) → 4-methylmorpholine - borane (1/1) (15648-16-5)

Guidance literature:

In neat (no solvent); High Pressure; pressure: 60kg/cm**2, 150-160°C, 5h;; fractionated distn.;;

Reference yield: 75.0%

sodium tetrahydroborate (16940-66-2) + N-methylmorpholine hydrochloride (3651-67-0) → 4-methylmorpholine - borane (1/1) (15648-16-5)

Guidance literature:

With 18-crown-6 ether; In diethyl ether; refluxing under Ar for 5 h; cooling, evapn. of solvent, sublimating residue under vac.;

DOI:10.1016/0022-328X(94)80072-3

upstream raw materials:

hydrogen

4-methyl-morpholine

diborane

boron trichloride

Downstream raw materials:

hydrogen

4-methyl-morpholine

triethyl borate

Refernces

• 1、 Brown, Herbert C.,Murray, Leo T.. "Molecular addition compounds. 9. Effect of structure on the reactivities of representative borane-amine complexes in typical reactions such as hydrolysis, hydroboration, and reduction". . p. 2746 - 2753. Retrieved 2008/10/08.