Benzenemethanamine, α-methyl-4-(2-methylpropyl)-, (S)- (9CI)

Base Information

• Chemical Name: Benzenemethanamine, α-methyl-4-(2-methylpropyl)-, (S)- (9CI)
• CAS No.: 164579-51-5
• Molecular Formula: C₁₂H₁₉N
• Molecular Weight: 177.29
• Hs Code.: 2921499090
• Mol file: 164579-51-5.mol

Synonyms:4-Isobutyl-a-methylbenzylamine

Chemical Property of Benzenemethanamine, α-methyl-4-(2-methylpropyl)-, (S)- (9CI)

Chemical Property:

• PSA: 26.02000
• LogP: 3.60510

Purity/Quality:

98%Min ^*data from raw suppliers

BENZENEMETHANAMINE, .ALPHA.-METHYL-4-(2-METHYLPROPYL)-, (S)- (9CI) 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenemethanamine, α-methyl-4-(2-methylpropyl)-, (S)- (9CI)

There total 3 articles about Benzenemethanamine, α-methyl-4-(2-methylpropyl)-, (S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ibuproxam (53648-05-8) → 1-(4-isobutyl-phenyl)-ethanone (38861-78-8) + ibuprofen (15687-27-1,58560-75-1) + 4'-(2-methylpropyl)acetophenone oxime (74305-51-4) + 4-(2-methylpropyl)phenylethylamine (164579-51-5)

Guidance literature:

at 110 ℃; for 24h; under 760 Torr; Product distribution; other temperature, reaction time;

DOI:10.1002/jps.2600690511

Reference yield:

4'-(2-methylpropyl)acetophenone oxime (74305-51-4) → 4-(2-methylpropyl)phenylethylamine (164579-51-5)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In ethanol; water;

Reference yield:

1-(4-isobutyl-phenyl)-ethanone (38861-78-8) → 4-(2-methylpropyl)phenylethylamine (164579-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol / 6 h / 60 °C

2: hydrogenchloride; palladium 10% on activated carbon; hydrogen / ethanol; water

With hydrogenchloride; palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; sodium acetate; In ethanol; water;

upstream raw materials:

ibuproxam

1-(4-isobutyl-phenyl)-ethanone

4'-(2-methylpropyl)acetophenone oxime

Refernces

• 1、 Chimichi,Innocenti,Orzalesi. "Thermal decomposition of ibuproxam". . p. 521 - 523. Retrieved 2007/10/02.