2-Amino-3-ethoxypyridine

Base Information

• Chemical Name: 2-Amino-3-ethoxypyridine
• CAS No.: 10006-74-3
• Molecular Formula: C7H10N2O
• Molecular Weight: 138.169
• Hs Code.: 2933399090
• Mol file: 10006-74-3.mol

Synonyms:Pyridine,2-amino-3-ethoxy- (7CI,8CI);2-Amino-3-ethoxypyridine;3-Ethoxy-2-aminopyridine;3-Ethoxypyridin-2-amine;

Chemical Property of 2-Amino-3-ethoxypyridine

Chemical Property:

• Vapor Pressure: 0.0227mmHg at 25°C
• Refractive Index: 1.548
• Boiling Point: 249.6 °C at 760 mmHg
• Flash Point: 104.7 °C
• PSA: 48.14000
• Density: 1.101 g/cm³
• LogP: 1.64370

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Ethoxy-2-pyridinamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Amino-3-ethoxypyridine

There total 6 articles about 2-Amino-3-ethoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-ethoxy-2-nitropyridine (74037-50-6) → 2-Amino-3-(ethoxy)pyridine (10006-74-3)

Guidance literature:

With iron; ammonium chloride; acetic acid; In ethanol; at 80 ℃; for 1h;

Reference yield:

3-ethoxy-2-nitropyridine (74037-50-6) → 2-Amino-3-(ethoxy)pyridine (10006-74-3) + 3-amino-2-nitropyridine (13269-19-7)

Guidance literature:

With ammonium hydroxide; at 140 - 150 ℃;

Reference yield:

2-amino-3-hydroxypyridine (16867-03-1) + sodium hydroxide,and + hexane (110-54-3) → 2-Amino-3-(ethoxy)pyridine (10006-74-3)

Guidance literature:

With sodium hydrogencarbonate; In methanol; water; dimethyl sulfoxide;

upstream raw materials:

3-ethoxy-2-nitropyridine

3-ethoxypyridine

2-amino-3-hydroxypyridine

hexane

Downstream raw materials:

2-amino-3-hydroxypyridine

sulfanilic acid-(3-ethoxy-[2]pyridylamide)

Refernces

• 1、 -. "Nicotinamide derivatives useful as PDE4 inhibitors". Page 17-18. . Retrieved 2010/02/10.
• 2、 -. "Imidazopyridine derivatives, their production, and pharmaceutical compositions containing them". . . Retrieved 2008/06/13.