16beta-(Phenylseleno)progesterone

Base Information

• Chemical Name: 16beta-(Phenylseleno)progesterone
• CAS No.: 74137-01-2
• Molecular Formula: C₂₅H₃₂O₂Se
• Molecular Weight: 443.488
• Mol file: 74137-01-2.mol

Synonyms:16beta-(Phenylseleno)progesterone

Chemical Property of 16beta-(Phenylseleno)progesterone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16beta-(Phenylseleno)progesterone

There total 9 articles about 16beta-(Phenylseleno)progesterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3β-hydroxy-16α-(phenylseleno)androst-5-en-17-ol (74137-06-7) → 16alpha-(Phenylseleno)progesterone (74137-01-2)

Guidance literature:

With aluminum tri-tert-butoxide; In cyclohexanone; toluene; for 0.166667h; Heating;

DOI:10.1021/jm00181a004

Reference yield:

C27H36O3Se → 16alpha-(Phenylseleno)progesterone (74137-01-2)

Guidance literature:

With toluene-4-sulfonic acid; In acetone; for 2h; Yield given; Heating;

DOI:10.1021/jm00181a004

Reference yield:

C27H36O3Se → 16beta-(Phenylseleno)progesterone (74137-01-2)

Guidance literature:

With toluene-4-sulfonic acid; In acetone; for 2h; Yield given; Heating;

DOI:10.1021/jm00181a004

upstream raw materials:

3β-hydroxy-16α-(phenylseleno)androst-5-en-17-ol

Phenylselenyl chloride

dehydroepiandrosterone

3β-hydroxy-16α-(phenylseleno)androst-5-en-17-one

Downstream raw materials:

testosterone

Refernces