DL-GLYCERALDEHYDE DIETHYL ACETAL

Base Information

• Chemical Name: DL-GLYCERALDEHYDE DIETHYL ACETAL
• CAS No.: 10487-05-5
• Molecular Formula: C7H16 O4
• Molecular Weight: 164.202
• Hs Code.: 2911000000
• Mol file: 10487-05-5.mol

Synonyms:1,2-Propanediol,3,3-diethoxy-, (?à)-;Glyceraldehyde, diethyl acetal, DL- (8CI); 1,2-Propanediol, 3,3-diethoxy-, DL-(8CI); 2,3-Dihydroxypropanal diethyl acetal; 3,3-Diethoxy-1,2-propanediol

Chemical Property of DL-GLYCERALDEHYDE DIETHYL ACETAL

Chemical Property:

• Vapor Pressure: 0.000508mmHg at 25°C
• Refractive Index: n20/D 1.414(lit.)
• Boiling Point: 136 °C / 27mmHg
• Flash Point: 126 °F
• PSA: 58.92000
• Density: 0.943 g/mL at 25 °C(lit.)
• LogP: -0.26130

Purity/Quality:

98%,99%, ^*data from raw suppliers

Di-glyceraldehydeDiethylAcetal ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 10-37/38-41
• Safety Statements: 16-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DL-GLYCERALDEHYDE DIETHYL ACETAL

There total 11 articles about DL-GLYCERALDEHYDE DIETHYL ACETAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

acrylaldehyde diethyl acetal (3054-95-3) → 3,3-diethoxypropane-1,2-diol (10487-05-5)

Guidance literature:

With potassium permanganate; In water; 1.) room temperature, 3 h, 2.) reflux, 1 h;

DOI:10.1016/S0968-0896(99)00065-6

Reference yield: 39.4%

2,3-epoxy-1,1-diethoxypropane (13269-77-7) → 3,3-diethoxypropane-1,2-diol (10487-05-5) + (R)-glycidaldehyde diethyl acetal (114882-92-7)

Guidance literature:

With Aspergillus niger epoxide hydrolase; In phosphate buffer; at 27 ℃; for 3.5h; pH=7.0;

DOI:10.1002/adsc.200606164

Reference yield:

ethanol (64-17-5) + Glyceraldehyde (56-82-6,367-47-5,26793-98-6) → 3,3-diethoxypropane-1,2-diol (10487-05-5)

Guidance literature:

With hydrogenchloride; at 0 ℃;

upstream raw materials:

3,3-diethoxy-2-chloro-propan-1-ol

acrylaldehyde diethyl acetal

ethanol

Glyceraldehyde

Downstream raw materials:

Glyceraldehyde

diethoxyacetaldehyde

hydroxy-pyruvaldehyde bis-phenylhydrazone

glycoaldehyde diethyl acetal

Refernces

• 1、 Zhao, Yu,Mitra, Aurpon W.,Hoveyda, Amir H.,Snapper, Marc L.. "Kinetic resolution of 1,2-diols through highly site- and enantioselective catalytic silylation". . p. 8471 - 8474. Retrieved 2008/09/18.
• 2、 Page, Patrick,Blonski, Casimir,Perie, Jacques. "Synthesis of phosphono analogues of dihydroxyacetone phosphate and glyceraldehyde 3-phosphate". . p. 1403 - 1412. Retrieved 2007/10/03.