meso-hexestrol dimethyl ether

Base Information

• Chemical Name: meso-hexestrol dimethyl ether
• CAS No.: 28231-25-6
• Molecular Formula: C₂₀H₂₆O₂
• Molecular Weight: 298.425
• Mol file: 28231-25-6.mol

Synonyms:meso-hexestrol dimethyl ether

Chemical Property of meso-hexestrol dimethyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of meso-hexestrol dimethyl ether

There total 88 articles about meso-hexestrol dimethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Diethylstilbestrol dimethyl ether (130-79-0) → racem.-3,4-bis-(4-methoxy-phenyl)-hexane (130-78-9,28199-75-9,28231-25-6,53584-73-9)

Guidance literature:

With palladium on activated charcoal; acetone; Hydrogenation;

DOI:10.1021/ja01865a069

Reference yield:

4-(1-bromo-propyl)-anisole (536-44-7) → meso-hexestrol dimethyl ether (28231-25-6) + racem.-3,4-bis-(4-methoxy-phenyl)-hexane (130-78-9,28199-75-9,28231-25-6,53584-73-9)

Guidance literature:

With nickel; Petroleum ether; at 75 - 80 ℃; weiteres Reagens: Wasser; unter Abdestillieren des Petrolaethers;

DOI:10.1021/jo01158a010

Reference yield:

4-(1-bromo-propyl)-anisole (536-44-7) → meso-hexestrol dimethyl ether (28231-25-6) + racem.-3,4-bis-(4-methoxy-phenyl)-hexane (130-78-9,28199-75-9,28231-25-6,53584-73-9)

Guidance literature:

With nickel; Petroleum ether; at 75 - 80 ℃; weiteres Reagens: Wasser; unter Abdestillieren des Petrolaethers;

DOI:10.1021/jo01158a010

upstream raw materials:

phosgene

diethyl ether

4-(1-bromo-propyl)-anisole

methylmagnesium bromide

Downstream raw materials:

3,4-bis-(3-bromo-4-methoxy-phenyl)-hexane

hexestrol

racem.-3,4-bis-(4-methoxy-phenyl)-hexane

erythro-4-(4-Hydroxyphenyl)-3-(4-methoxyphenyl)-hexane

Refernces

• 1、 Schloegl, Karl,Weissensteiner, Walter. "Syntheses of 1,2-Diferrocenylethanes and 1,2-Diarylethanes by Titanium-Induced Reductive Coupling of the Lithium Salts of Ferrocenyl (and Aryl) Carbinols". . p. 50 - 53. Retrieved 2007/10/02.