Drometrizole trisiloxane

Base Information

• Chemical Name: Drometrizole trisiloxane
• CAS No.: 155633-54-8
• Molecular Formula: C24H39 N3 O3 Si3
• Molecular Weight: 501.848
• Hs Code.: 2933997500
• European Community (EC) Number: 422-940-4,919-634-2,687-624-2
• UNII: HC22845I1X
• DSSTox Substance ID: DTXSID40431753
• Nikkaji Number: J1.361.521G
• Wikipedia: Drometrizole_trisiloxane
• Wikidata: Q5308268
• Metabolomics Workbench ID: 152729
• Mol file: 155633-54-8.mol

Synonyms:drometrizole trisiloxane;Mexoryl XL;Silatrizole

Chemical Property of Drometrizole trisiloxane

Chemical Property:

• Boiling Point: 530.6±60.0 °C(Predicted)
• PKA: 8.36±0.50(Predicted)
• PSA: 69.40000
• Density: 1.06±0.1 g/cm3(Predicted)
• LogP: 6.38810
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 501.22992172
• Heavy Atom Count: 33
• Complexity: 613

Purity/Quality:

98%, ^*data from raw suppliers

Drometrizole trisiloxane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C(=C1)N2N=C3C=CC=CC3=N2)O)CC(C)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C
• Uses: drometrizole trisiloxane is a uV absorber/uV filter, it provides uVBand some uVA-spectrum protection. Drometrizole Trisiloxane is used in the synthesis of UV light absorbers and filters for polyester fibers and suncare formulations.

Technology Process of Drometrizole trisiloxane

There total 2 articles about Drometrizole trisiloxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1,1,1,3,5,5,5-heptamethyltrisiloxan (1873-88-7) + 2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-(2-methylprop-2-enyl)phenol (98809-58-6) → drometrizole trisiloxane (155633-54-8)

Guidance literature:

platinum⁽⁰⁾-1,3-divinyl-1,1,3,3-tetramethyldisiloxane complex; In ethyl acetate; at 50 - 60 ℃; Product distribution / selectivity; Inert atmosphere; Reflux;

Reference yield:

→ drometrizole trisiloxane (155633-54-8)

Guidance literature:

upstream raw materials:

1,1,1,3,5,5,5-heptamethyltrisiloxan

2-(2H-1,2,3-benzotriazol-2-yl)-4-methyl-6-(2-methylprop-2-enyl)phenol

Refernces

• 1、 -. "PROCESS FOR PREPARING 2-HYDROXYPHENYL BENZOTRIAZOLE SILOXANE COMPOUNDS". Paragraph 0113. . Retrieved 2013/08/15.
• 2、 -. "ALPHA-AMINO ACID DERIVATIVES FOR IMPROVING SOLUBILITY". . . Retrieved 2011/04/13.