2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer)

Base Information

• Chemical Name: 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer)
• CAS No.: 1215-55-0
• Molecular Formula: C₁₃H₁₁N₃O
• Molecular Weight: 225.25
• Mol file: 1215-55-0.mol

Synonyms:2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer)

Chemical Property of 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer)

There total 6 articles about 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

pyridine-2-carbaldehyde (1121-60-4) + benzoic acid hydrazide (613-94-5) → 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer) (1215-55-0)

Guidance literature:

In ethanol; for 6h; Reflux;

DOI:10.1021/ja504813r

Reference yield:

(E)-4-(dimethylamino)-N'-(pyridin-2-ylmethylene)benzohydrazide + benzoic acid hydrazide (613-94-5) → 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer) (1215-55-0) + 4-(dimethylamino)benzohydrazide (19353-92-5)

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In d⁽⁴⁾-methanol; at 45 ℃;

DOI:10.1002/chem.201002308

Reference yield:

2-pyridyl carboxaldehyde benzoylhydrazone (Z-isomer) → 2-pyridyl carboxaldehyde benzoylhydrazone (E-isomer) (1215-55-0)

Guidance literature:

Reflux;

DOI:10.1002/chem.201002308

upstream raw materials:

pyridine-2-carbaldehyde

benzoic acid hydrazide

benzoic acid

benzoic acid methyl ester

Downstream raw materials:

benzoic acid hydrazide

C₂₆H₂₂AgN₆O₂⁽¹⁺⁾*ClO₄^(1-)

Refernces

• 1、 Singh, Yogendra,Patel,Patel, Satish Kumar,Patel, Abhay Kumar,Patel,Singh, Rita,Butcher,Jasinski, Jerry P.,Gutierrez. "Experimental and quantum computational study of two new bridged copper(II) coordination complexes as possible models for antioxidant superoxide dismutase: Molecular structures, X-band electron paramagnetic spectra and cryogenic magnetic properties". . p. 155 - 171. Retrieved 2019.
• 2、 Patel, Ram N.,Patel, Dinesh K.,Shukla, Krishna K.,Singh, Yogendra. "Carboxylate-bridged copper(II) complexes: Synthesis, crystal structures, and superoxide dismutase activity". . p. 4131 - 4143. Retrieved 2013.
• 3、 Fekri, Roghayeh,Salehi, Mehdi,Asadi, Asadollah,Kubicki, Maciej. "Synthesis, characterization, anticancer and antibacterial evaluation of Schiff base ligands derived from hydrazone and their transition metal complexes". . p. 245 - 254. Retrieved 2018/10/02.