5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl

Base Information

• Chemical Name: 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl
• CAS No.: 696612-61-0
• Molecular Formula: C₆₂H₇₆N₂O₄Si₂
• Molecular Weight: 969.467
• Mol file: 696612-61-0.mol

Synonyms:5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl

Chemical Property of 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl

There total 5 articles about 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dibenzyloxybenzaldehyde (5447-02-9) → 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl (696612-61-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 98 percent / ammonium acetate; acetic acid / 0.67 h / Heating

2: 97 percent / acetic acid; HNO₃ / H₂O / 2 h / 20 °C

3: 61 percent / iron; acetic acid; SiO₂ / benzene; cyclohexane / 0.5 h / Heating

4: 95 percent / n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C

5: 100 percent / iodine; Hg(OAc)2 / CH₂Cl₂ / 2 h / 0 - 20 °C

6: 68 percent / tetrakis(dimethylamino)ethylene; Pd(PhCN)2Cl₂ / dimethylformamide / 1.5 h / 50 °C

With ammonium acetate; bis(benzonitrile)palladium(II) dichloride; n-butyllithium; Tetrakis(dimethylamino)ethylen; mercury(II) diacetate; iodine; nitric acid; silica gel; iron; acetic acid; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; benzene; 1: Henry reaction;

DOI:10.1016/j.tet.2004.02.043

Reference yield:

5,6-dibenzyloxyindole (4790-19-6) → 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl (696612-61-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C

2: 100 percent / iodine; Hg(OAc)2 / CH₂Cl₂ / 2 h / 0 - 20 °C

3: 68 percent / tetrakis(dimethylamino)ethylene; Pd(PhCN)2Cl₂ / dimethylformamide / 1.5 h / 50 °C

With bis(benzonitrile)palladium(II) dichloride; n-butyllithium; Tetrakis(dimethylamino)ethylen; mercury(II) diacetate; iodine; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2004.02.043

Reference yield:

(E)-3,4-dibenzyloxy-β-nitrostyrene (1699-54-3) → 5,5',6,6'-tetrabenzyloxy-N,N'-di(triisopropylsilyl)-3,3'-biindolyl (696612-61-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 97 percent / acetic acid; HNO₃ / H₂O / 2 h / 20 °C

2: 61 percent / iron; acetic acid; SiO₂ / benzene; cyclohexane / 0.5 h / Heating

3: 95 percent / n-butyllithium / tetrahydrofuran; hexane / 2 h / -78 °C

4: 100 percent / iodine; Hg(OAc)2 / CH₂Cl₂ / 2 h / 0 - 20 °C

5: 68 percent / tetrakis(dimethylamino)ethylene; Pd(PhCN)2Cl₂ / dimethylformamide / 1.5 h / 50 °C

With bis(benzonitrile)palladium(II) dichloride; n-butyllithium; Tetrakis(dimethylamino)ethylen; mercury(II) diacetate; iodine; nitric acid; silica gel; iron; acetic acid; In tetrahydrofuran; hexane; dichloromethane; cyclohexane; water; N,N-dimethyl-formamide; benzene;

DOI:10.1016/j.tet.2004.02.043

upstream raw materials:

3,4-dibenzyloxybenzaldehyde

5,6-dibenzyloxyindole

(E)-3,4-dibenzyloxy-β-nitrostyrene

benzyl chloride

Downstream raw materials:

5,5',6,6'-tetrabenzyloxy-3,3'-biindolyl

Refernces