cinnamyl 2-bromopropanoate

Base Information

• Chemical Name: cinnamyl 2-bromopropanoate
• CAS No.: 40630-85-1
• Molecular Formula: C₁₂H₁₃BrO₂
• Molecular Weight: 269.138
• Mol file: 40630-85-1.mol

Synonyms:cinnamyl 2-bromopropanoate

Chemical Property of cinnamyl 2-bromopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cinnamyl 2-bromopropanoate

There total 2 articles about cinnamyl 2-bromopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-Phenylpropenol (104-54-1) + α-bromopropionyl bromide (563-76-8) → cinnamyl 2-bromopropanoate (40630-85-1)

Guidance literature:

With pyridine; dmap; In dichloromethane; at 0 ℃; for 0.666667h; Inert atmosphere;

DOI:10.1016/j.tet.2011.03.079

Reference yield:

→ 2-Brompropionsaeurecinnamylester (40630-85-1)

Guidance literature:

/BRN= 514397/, Ph-CH=CH-CH2OH;

DOI:10.1039/c39730000117

Reference yield: 100.0%

cinnamyl 2-bromopropanoate (40630-85-1) → cinnamyl propionate (78761-38-3,103-56-0)

Guidance literature:

With indium(III) chloride; indium; chloro-trimethyl-silane; triethylamine; acetonitrile; at 10 - 30 ℃; Inert atmosphere; Sonication;

DOI:10.1016/j.tet.2011.03.079

upstream raw materials:

3-Phenylpropenol

α-bromopropionyl bromide

Downstream raw materials:

2-methyl-3-phenyl-pent-4-enoic acid

cinnamyl propionate

Refernces

• 1、 Ishihara, Jun,Watanabe, Yuki,Koyama, Noriko,Nishino, Yukihiro,Takahashi, Keisuke,Hatakeyama, Susumi. "Indium-mediated Reformatsky-Claisen rearrangement". experimental part. p. 3659 - 3667. Retrieved 2011/06/21.