Fmoc-gabapentin N,N-dimethylaminoethyl ester

Base Information

• Chemical Name: Fmoc-gabapentin N,N-dimethylaminoethyl ester
• CAS No.: 1152425-51-8
• Molecular Formula: C₂₈H₃₆N₂O₄
• Molecular Weight: 464.605
• Mol file: 1152425-51-8.mol

Synonyms:Fmoc-gabapentin N,N-dimethylaminoethyl ester

Chemical Property of Fmoc-gabapentin N,N-dimethylaminoethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Fmoc-gabapentin N,N-dimethylaminoethyl ester

There total 1 articles about Fmoc-gabapentin N,N-dimethylaminoethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-(N,N-dimethylamino)ethanol (108-01-0) + Fmoc-gabapentin (882847-19-0) → Fmoc-gabapentin N,N-dimethylaminoethyl ester (1152425-51-8)

Guidance literature:

Fmoc-gabapentin; With dmap; 2,2'-dipyridyl carbonate; In toluene;

2-(N,N-dimethylamino)ethanol; In toluene; at 20 ℃; for 24h;

DOI:10.1016/j.tetlet.2009.02.125

Reference yield:

Fmoc-gabapentin N,N-dimethylaminoethyl ester (1152425-51-8) + methyl iodide (74-88-4) → Fmoc-gabapentin-choline (1152425-52-9)

Guidance literature:

In chloroform; at 20 ℃; for 24h;

DOI:10.1016/j.tetlet.2009.02.125

upstream raw materials:

2-(N,N-dimethylamino)ethanol

Fmoc-gabapentin

Downstream raw materials:

Fmoc-gabapentin-choline

Refernces