quinolin-2-ylmethyl benzoate

Base Information

• Chemical Name: quinolin-2-ylmethyl benzoate
• CAS No.: 61831-29-6
• Molecular Formula: C₁₇H₁₃NO₂
• Molecular Weight: 263.296
• Mol file: 61831-29-6.mol

Synonyms:quinolin-2-ylmethyl benzoate

Chemical Property of quinolin-2-ylmethyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of quinolin-2-ylmethyl benzoate

There total 12 articles about quinolin-2-ylmethyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-Chloroquinoline (612-62-4) + [(benzoyloxy)methyl]zinc iodide (14135-39-8) → quinolin-2-ylmethyl benzoate (61831-29-6)

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃;

DOI:10.1055/s-2008-1032084

Reference yield: 86.0%

2-methylquinoline (91-63-4) + benzyl alcohol (100-51-6,185532-71-2) → quinolin-2-ylmethyl benzoate (61831-29-6)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; at 90 ℃; for 12h; Reagent/catalyst;

DOI:10.1039/c6ra26387a

Reference yield: 76.0%

2-methylquinoline (91-63-4) + benzaldehyde (100-52-7) → quinolin-2-ylmethyl benzoate (61831-29-6)

Guidance literature:

With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide; In water; at 80 ℃; for 12h; Solvent; Reagent/catalyst; Mechanism; Inert atmosphere;

DOI:10.1039/c2cc35450k

upstream raw materials:

quinolin-2-ylmethanol

benzyl chloride

benzoyl chloride

sodium benzoate

Downstream raw materials:

quinolin-2-ylmethanol

2-methylquinoline

Refernces

• 1、 Wang, Chang-Sheng,Roisnel, Thierry,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois. "Synthesis of 2-Pyridinemethyl Ester Derivatives from Aldehydes and 2-Alkylheterocycle N-Oxides via Copper-Catalyzed Tandem Oxidative Coupling-Rearrangement". supporting information. p. 6720 - 6723. Retrieved 2017/12/26.
• 2、 Hasník, Zbyněk,?ilhár, Peter,Hocek, Michal. "Hydroxymethylations of aryl halides by Pd-catalyzed cross-couplings with (benzoyloxy)methylzinc iodide - Scope and limitations of the reaction". . p. 543 - 546. Retrieved 2008/12/22.