C₁₅H₁₈N₂O₄S₂

Base Information

• Chemical Name: C₁₅H₁₈N₂O₄S₂
• CAS No.: 123420-33-7
• Molecular Formula: C₁₅H₁₈N₂O₄S₂
• Molecular Weight: 354.451
• Mol file: 123420-33-7.mol

Synonyms:C₁₅H₁₈N₂O₄S₂

Chemical Property of C₁₅H₁₈N₂O₄S₂

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₅H₁₈N₂O₄S₂

There total 1 articles about C₁₅H₁₈N₂O₄S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 3-amino-5-phenylthiophene-2-carboxylate (100063-22-7) + isopropylsulfamoyl chloride (26118-67-2) → C15H18N2O4S2 (123420-33-7)

Guidance literature:

In benzene; at 80 ℃; for 4h;

DOI:10.1055/s-1989-27222

Reference yield: 98.0%

C15H18N2O4S2 (123420-33-7) → C14H16N2O4S2 (123420-35-9)

Guidance literature:

With potassium hydroxide; at 25 ℃; for 4h;

DOI:10.1055/s-1989-27222

Reference yield:

C15H18N2O4S2 (123420-33-7) → 3-Isopropyl-2,2-dioxo-6-phenyl-2,3-dihydro-1H-2λ6-thieno[3,2-c][1,2,6]thiadiazin-4-one (123420-37-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / 5percent aq. KOH / 4 h / 25 °C

2: 85 percent / CF₃COOH, (CF₃CO)2O / 3 h / 25 °C

With potassium hydroxide; trifluoroacetic acid; trifluoroacetic anhydride;

DOI:10.1055/s-1989-27222

upstream raw materials:

methyl 3-amino-5-phenylthiophene-2-carboxylate

isopropylsulfamoyl chloride

Downstream raw materials:

C₁₄H₁₆N₂O₄S₂

3-Isopropyl-2,2-dioxo-6-phenyl-2,3-dihydro-1H-2λ⁶-thieno[3,2-c][1,2,6]thiadiazin-4-one

Refernces