4-(2-methoxyphenyl)dibenzofuran

Base Information

• Chemical Name: 4-(2-methoxyphenyl)dibenzofuran
• CAS No.: 92185-79-0
• Molecular Formula: C₁₉H₁₄O₂
• Molecular Weight: 274.319
• Mol file: 92185-79-0.mol

Synonyms:4-(2-methoxyphenyl)dibenzofuran

Chemical Property of 4-(2-methoxyphenyl)dibenzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(2-methoxyphenyl)dibenzofuran

There total 4 articles about 4-(2-methoxyphenyl)dibenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-dibenzofurylboronic acid (100124-06-9) + 2-Chloroanisole (766-51-8) → 4-(2-methoxyphenyl)dibenzofuran (92185-79-0)

Guidance literature:

With sodium hydroxide; polyaniline-supported palladium; In water; at 100 ℃; for 6h;

DOI:10.1002/anie.200701389

Reference yield:

4-dibenzofurylboronic acid (100124-06-9) + 2-bromoanisole (578-57-4) → 4-(2-methoxyphenyl)dibenzofuran (92185-79-0)

Guidance literature:

With tetra-butylammonium acetate; Pd EnCat-30^TM; In ethanol; at 120 ℃; for 0.166667h; microwave irradiation;

DOI:10.1002/chem.200501400

Reference yield:

dibenzofuran (132-64-9,214827-48-2) → 4-(2-methoxyphenyl)dibenzofuran (92185-79-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) 2.4 M BuLi / 1,) THF, hexane, 25 deg C, 5 h; 2.) THF, 25 deg C, 2 h

2: 1.) Mg; 2.) Ni6H₅)3>2Cl₂ / 1.) Et₂O, reflux, 12 h; 2.) Et₂O, reflux, 24 h

With bis(triphenylphosphine)nickel(II) chloride; n-butyllithium; magnesium;

DOI:10.1021/ja00335a049

upstream raw materials:

4-bromodibenzofuran

2-bromoanisole

4-dibenzofurylboronic acid

dibenzofuran

Downstream raw materials:

4-(2-hydroxyphenyl)dibenzofuran

Refernces

• 1、 Baxendale, Ian R.,Griffiths-Jones, Charlotte M.,Ley, Steven V.,Tranmer, Geoffrey K.. "Microwave-assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous-flow transformations". . p. 4407 - 4416. Retrieved 2008/02/07.